Genetic explanation for OCD
- Created by: Ellie Whitehead
- Created on: 20-11-14 16:10
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- Genetic explanation for OCD
- Genetic Hypothesis
- More closely related the family member is to the OCD patient the greater their chance of inheriting it.
- We inherit a predisposition to develop anxiety disorders.
- We don't know that much about genetic factors which contribute to OCD. May influence brain structure in some way.
- Family studies
- (Genetic hypothesis) 1st degree relatives share 50% of genes.
- Studies compare rates of OCD in first degree relatives of someone with OCD (proband) with similar families without OCD.
- Twin Studies
- Compare differences in concordance rate for identical (MZ) and fraternal (DZ) twins.
- Both share the same environment but only MZ twins share the same genetic make up.
- If OCD is genetic then MZ twins should be more concordant.
- Compare differences in concordance rate for identical (MZ) and fraternal (DZ) twins.
- General AO2
- Pieces of research for Family studies
- Pauls et ak
- Nestadt et al
- Pieces of research for twin studies
- Carey and Gottesman
- Lambert and Kinsley
- General criticisms
- Twin and family studies have not always found the same concordance rates.
- Contradictory studies- Andrews found no evidence for higher concordance rates in MZ twins.
- Maybe we inherit a predisposition to anxiety rather than OCD specifically
- Evolutionary explanation that it is hard wired into our brains to be obsessive about something.
- No specific gene has been identified to cause OCD
- Pieces of research for Family studies
- Issues debates and approaches
- Nature vs Nurture
- Family studies and twin studies both disregard the fact that participants share the same environment meaning you cannot disentangle from nurture.
- Reductionism
- This is over-simplified to genes.
- Nature vs Nurture
- Genetic Hypothesis
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