DNA replication

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  • DNA replication
    • semi-conservative replication
      • half of the strands in each new DNA molecule are from the original DNA molecule
    • 1. double helix unwinds
      • 2. the H bonds are broken between complementary bases by DNA helicase
        • 3. each strand acts as a template. free nucleotides pair with complementary bases
          • 4. condensation reaction joins the nucleotides of nw strands together (catalysed by DNA polymerase)
            • 5. new H bonds form between bases
    • each end of a DNA strand is slightly different in its structure. One end is called 3' and the other is 5'
    • anti-parallel strands
    • Meselon and Stahl provided evidence for semi-conservative replication


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