clostridial disease

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  • clostridial disease
    • definition
      • gram +ve, fatal tocins resulting in GI disease and death
      • diet change, parasites, injury and stress
      • soil, rotting veg, commensal of GIT, immunocompromised
    • 3 subgroups
      • histotoxic (clostridium type B
        • lamb dysentry
        • haemorrhagic enteritis
        • ulceration of SI
        • collapse
        • death
      • neutrophilic
      • enterotoxic - C.perfringes
        • type C= struck
          • neonates and adult sheep around spring grass
          • necrotic enteritis and ulceration
        • type D= pulpy kidney
          • most common
          • seen in lambs
          • often found dead
          • rapid kidney autolysis
    • clinical signs
      • sudden death
      • neuro signs
      • diarrhoea
    • diagnostics
      • enterotoxic
        • PM= autolysed kidneys or ulcerated GIT
        • isolation organism not useful as commensal- need to look at pathology
        • ELISA of tissue to see toxin
    • treatment
      • early intervention with penicillin
      • NSAIDS
      • poor px
    • prevention
      • vaccination
      • reduced concentrate feeding
      • remove from affected pasture
      • Untitled

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