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  • Bio assessment 1
    • topic 1
      • triglycerides are formed by the condensation of 3 fatty acids with 1 mol of glycerol  joined with an ester bond
      • phospholipids have 1 glycerol and phosphate and 2 fatty acids, joined by an ester bond
        • they have hydrophilic head and hydrophobic tails
        • allows them to form a bilayer which has the hydrophilic heads facing outwards and the hydrophobic tails facing inwards
      • primary structure is the specific order of A.A, this effects all orders of structure, secondary = h bonding at certain regions, tertiary = specific 3D shape due to interactions between R groups
        • specific structure needed for certain functions- eg enzymes and antibodies
      • enzymes have a specific tertiary structure, meaning active site is only complementary to one substrate, cannot form E-S  complexes
      • ph can effect ionic bonding in tertary s so can denature
        • tem[perature can increase Ke of  particles = more collisions
        • more enzyme / sub = faster ROR
        • inhibitors reduce roR AS PREVENT E-S COMPLEXES
    • Topic 2
      • nucleus stores dna and genetic info, RER protein synthesis + mod, SER lipid synthesis and mod , golgi- transport and mod , lysosomes - break down cell debris
        • mitocondria produce ATP via respiration and chloroplasts produce glucose via photo
      • light microscopes use light which had a longer wave length = lower res + mag
        • TEM+SEM use electrons which have a smaller wavelength
          • vacuum = dead
      • cell membrane = phospholipid bilayer - lets in  non-polar small ,has proteins embedded eg interregnal and peripheral
      • antigen regonition is improtant so that the immune system recognises non-slef antigens on pathogens and does not attak its own cells
      • the phagocyte follows chem trail of the pathogen and engulfs it , forms phagosome around it , lysosomes bind and fuse wit it relapsing enzymes which break down pathogen
      • antibody is a proton with a specic tertary structure, produced by a b cell, which bind to a specific pathogen
      • hiv is a retor virus , bind to CD4 protein on Th cell, injects nulecic acid into cell - reverse transcriptase rna to DNA and integrates incrops - cell synthesis proteins
        • HVI causes AIDs when enough Th cells are killed
      • micleles move towards the membrane and FA and mg diffuse through the membrane, re assosiate into tris and assosited with protein to form a chylomicron at golgi - vesicle out via exocytosis
    • enzymes are used to hydrolyse large insoluble mols to smaller soluble ones - exdopeptideases and end and di
      • multiple enzymes used to increse ror
    • topic 3
      • enzymes are used to hydrolyse large insoluble mols to smaller soluble ones - exdopeptideases and end and di
        • multiple enzymes used to increse ror
      • micleles move towards the membrane and FA and mg diffuse through the membrane, re assosiate into tris and assosited with protein to form a chylomicron at golgi - vesicle out via exocytosis
    • topic 4
      • an intron is  a non-coding section of DNA where as an exon is a coding section of DNA
      • DNA helicase breaks hydrogen bonds between complementary base pairs
        • with one strand acting as a template, free RNA nucleotides attach in their complementary pairs froming hydrogen bonds
          • RNA polymerase then condenses the nucleotides forming  phosphodiester  bonds
            • pre-mRNA is then spliced removing the introns
      • mutations occur spontaneously and normally during DNA replication or cell divsion
      • deleations can lead to a frame shift, effecting multiple codons, chnaging the over all tertary structure
        • substitutions -can lead to a change in protein structure, however most of the time as DNA code is degernerate, a sub often codes for the same amino acid
      • Binomial name system = genus and species
      • Quantitative investigations
        • use large and random sampling to ensure sample is reprsentivive
          • systematic = belt transect
            • there is a gradual change from one side of a habitat to another, like the change in light between the outer edges of a forest to the centre.
          • randome eg quadrats
            • estimating pop sizes or distribution
        • SD= spread of data about the mean, indicating sig diffs
      • directional selection- selects for one extreme of the mean due to change in environment
        • eg ar bacteria, spontaneous mutation results in resistance - if in environment where antibiotic is used, others die out leaving only resistant to divide + allele F increases
      • stabilising selection- when no change in environment -mean is selected for
        • eg birth weights - narrow margin as both extremes are selected against for optimum birth weight

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