A rise in urine osmolarity is caused by osmotic diuretics (increased urine volume), what is the blockade of hormone receptors or ion channels caused by?
K+ sparing diuretics
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blocking what actions in the late renal tubule impacts on the 5% (variable) sodium reabsorption regulated by this hormone, which leaves more sodium in the filtrate; and this translates into a small rise in urine volume (a very low ceiling diuresis).
aldosterone
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an osmotic diuretic like mannitol, freely enter the renal filtrate, are not reabsorbed and essentially act as “what magnets”
water
3 of 13
what is a mainstream approach to preventing sodium reabsorption and eliciting natriuresis, with attendant diuresis
The inhibition of tubular ion cotransporters i.e. either the NaK2Cl or NaCl cotransporter
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how do osmotic diuretics like mannitol Oppose water reabsorption at multiples sites around nephron
promote sodium loss by disrupting tubular sodium gradients
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Loop diuretics, named after their site of action to inhibit NaK2Cl cotransport in the loop of Henle, include what. select wrong drug
lidonemide
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Their large scale diuretic effect stems from what. select incorrect answer
non-diuresis
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loop diuretics can lead to disturbances such as: select untrue answer
hypoglycaemia
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what inhibit NaCL co transport in early distal tubule?
thiazide diuretics
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thiazide-like agents include
bendroflumethiazide
10 of 13
Carbonic anhydrase (CA) inhibitor diuretics are inhibitory enzymes responsible for what?
Na+ + HCO3- reabsorption in PCT
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ADH receptor antagonists as “aquaretics”, is capable of producing water loss without natriuresis, what receptor in kidney can it block?
ADH V2 receptor
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blocking ADH V2 receptor in kidney then prevents what?
ADH-mediated water reabsorption in the collecting duct
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Other cards in this set
Card 2
Front
blocking what actions in the late renal tubule impacts on the 5% (variable) sodium reabsorption regulated by this hormone, which leaves more sodium in the filtrate; and this translates into a small rise in urine volume (a very low ceiling diuresis).
Back
aldosterone
Card 3
Front
an osmotic diuretic like mannitol, freely enter the renal filtrate, are not reabsorbed and essentially act as “what magnets”
Back
Card 4
Front
what is a mainstream approach to preventing sodium reabsorption and eliciting natriuresis, with attendant diuresis
Back
Card 5
Front
how do osmotic diuretics like mannitol Oppose water reabsorption at multiples sites around nephron
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