Physiology - synaptic transmission

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  • Created by: m_watson
  • Created on: 11-04-16 13:20
What is a contact between two neurons?
synapse
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what type of synapse depolarises the cell?
excitatory
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What type of synapse hyperpolarises the cell?
inhibitory
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What type of synapse is associated with the secretion of a neurotransmitter?
chemical
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What type of synapse is associated with fast transmission via gap junctions?
electrical
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how does the neurotransmitter travel across the synaptic cleft?
diffusion
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what is the synapse called that joins an axon to a cell body?
axosomatic
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what is the synapse called that joins an axon to a dendrite?
axodendritic
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what is the synapse called that joins an axon to an axon?
axoaxonic
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how does the neurotransmitter leave the pre-synaptic cell?
exocytosis
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what type of receptor are the acetylcholine receptors on the post-synaptic cell?
nicotinic
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what enzyme breaks down acetylcholine?
acetylcholinesterase
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acetylcholine is broken down into choline and ...?
acetate
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within the nerve terminal choline is acetylated by which enzyme to form acetylcholine?
choline acetyltransferase
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when an ion channel is controlled directly by the arrival of a neurotransmitter molecule - it is described as?
ionotropic
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are ligand-gated ion channels fast or slow?
fast
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when a receptor causes an indirect response within the cell (for example via second messengers like G- protein coupling) and are SLOW - what are they described as?
metabotropic
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the action potential generated by a depolarisation is known as?
excitatory post-synaptic potential
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what type of synaptic transmission causes potassium or chlorine channels to open?
inhibitory
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which type of class of neurotransmitter is the most abundant?
amino acids
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when the synaptic potentials summate by the addition of all the low-level signals - what is this called?
temporal summation
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when the synaptic potentials summate by the balance of all the inhibitory and excitatory inputs - what is this called?
spatial summation
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this agent attacks the fusion protein (SNAP - 25) at the neuromuscular junction - it prevents the release of ACh.
botulinum toxin
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this agent is in poison darts and prevents the uptake of Ach by the post-synaptic receptors
strychnos toxifera
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what type of neurotransmitter is acetylcholine?
ester
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what type of neurotransmitter is glutamic acid and GABA?
amino acid
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what type of neurotransmitter is adrenaline, dopamine, serotonin
amine
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what type of neurotransmitter is somatostatin, ADH
peptide
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what type of neurotransmitter is nitric oxide?
inorganic gas
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Card 2

Front

what type of synapse depolarises the cell?

Back

excitatory

Card 3

Front

What type of synapse hyperpolarises the cell?

Back

Preview of the front of card 3

Card 4

Front

What type of synapse is associated with the secretion of a neurotransmitter?

Back

Preview of the front of card 4

Card 5

Front

What type of synapse is associated with fast transmission via gap junctions?

Back

Preview of the front of card 5
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