Anatomically localizing particular molecules to particular cells that can be used for localizing any molecule that a specific antibody can be generated.
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What are the major neurotransmitters?
Amino acids, amine and peptides
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What are the two types of synapses?
Electrical and Chemical
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Where do electrical synapses work?
When there is a gap junction, so the two membranes are only separated by 3 nm.
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Where do chemical synapses work?
Where the two membranes are separated by 20nm
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What are axondendritic synapses?
When the postsynaptic membrane is on a dendrite.
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What are axosomatic synapses?
When the postsynaptic membrane is on a cell body.
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What are axoaxonic synapses?
When the postsynaptic membrane is on another axon.
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What are dendrodendritic synapses?
These only occur on specialized neurons that have dendrites forming synapses.
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What is a Gray's type 1 synapse?
Asymmetrical and usually excitatory.
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What is a Gray's type 2 synapse?
Symmetrical and usually inhibitory.
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What neurotransmitters does fast synaptic transmission use?
At CNS synapses-Glutamate, GABA, Glycine, and at neuromuscular junctions uses Acetylcholine
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What is an excitiatory post synaptic potential?
A transient postsynaptic membrane depolarization caused by presynaptic release of neurotransmitter.
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What is an inhibitory post synaptic potential?
Transient hyperpolarization of postsynaptic membrane potential caused by presynaptic release of neurotransmitter
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What do receptor antagonists do?
Bind to receptors, blocking the action of the transmitter
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What do receptor agonists do?
Bind to receptors, mimiking the neurotransmitter release.
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What is Spatial EPSP summation?
The adding together of EPSPs generated at the same time at different synapses on a dendrite
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What is Temporal EPSP summation?
The adding together of EPSPs generated at the same synapse when occuring in rapid succession
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