Musculoskeletal disease 3

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what is hyperparathyroidsm and what are the symptoms
- Pathophysiology: excess parathyroid hormone, usually adenoma in parathyroid gland 0.1% of population
- Symptoms: hypercalcaemia (confusion, depression, constipation, abdominal pains, bone pains, kidney stones) untreated hypercalcaemia: cardiac dysrhythm
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what are the dental considerations for hyperparathyroidms
effects of bone resorption (giant cell lesions, loss of lamina dura around roots), may have had treatment with bisphosphonates
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vitamin D deficiency causes...
in adults this condition is called
in children this condition is called
poor bone mineralisation
adults: osteomalacia
kids: rickets
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what are the symptoms of vitamin d deficiency
- Diffuse bony pains
- Proximal muscle weakness
- Bone fragility due to defective mineralisation
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what is Paget's disease
abnormal bone remodelling- abundant new bone formation, structurally abnormal, prone to fracture
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what are the symptoms of Paget's disease
most completely asymptomatic, bone deformities, enlargement of skulls, nerve compression (leads to deafness and spinal cord compression), fractures
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what are the dental consideration of paget's disease
Initial diagnosis:
 recognition of radiological features, recognition of dental changes
Established diagnosis:
 care with surgery to bone (infection and fracture risk)
 May be hypercementosis of teeth making extraction difficult
 Awareness of osteosa
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what is osteoporosis
loss of bone mass (all components not just calcium) + increased fracture risk
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what are the dental considerations of osteoporosis
- Osteoporosis- bisphosphonates/denosumab
Osteonecrosis of the jaw. The risk is higher with: IV bisphosphonates cf oral. Conditions other than osteoporosis
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what are the dental considerations for hyperparathyroidms

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effects of bone resorption (giant cell lesions, loss of lamina dura around roots), may have had treatment with bisphosphonates

Card 3

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vitamin D deficiency causes...
in adults this condition is called
in children this condition is called

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what are the symptoms of vitamin d deficiency

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Card 5

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what is Paget's disease

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