Immunology of Allergy - BM5 RCR1

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P G Y C Y U C I I N F M V K V Y E T A G O
H N M Y F Y J R H N E Y S Y N F E E R Y M
W C M C M B L T D Q G R B F U S D O A B X
H Q R L T O S U X R P X P H A E Q S C Q Y
A X S O U N I E R O S I I M L T B I H D H
L F L O Q E D F E S N T Y E V D U N I R H
X X L X S M C L V Q K H U K F E W O D X U
H S E Y F A P E W P C K D P O S S P O X E
R M C G N R A W C E O H V H C A K H N O C
S J T E B R V A S T T L O W U E J I I H O
G R S N A O L A R U A P M I L R I L C M S
Y E A A D W T I F T E L N A H C M M A R P
M W M S C P E O E B F I F T O E K E C V D
I B G E Y N A P R F K F C U O D T D I C J
V J I R E J H R Q U P O E G H P Q I D M L
A F T S V A D P M W X V N Y U R Y A W H F
G E Y W S P C D P V D G J Q N A N T I Q Y
E O Y E G O B L E T C E L L S H U O T W M
E R L X I H O R P Q P M K J A S J R E E A
J F E P Q M G T Q G X B J T B Y F S Q F A
W T I G K X A P L X B T W B I I I U Q A D

Clues

  • As allergies progress to allergic asthma, mast cell mediators become less important. What takes their place? (10, 9)
  • As well as histamine granules, mast cells contain proteolytic enzymes. Name two. (8, 7)
  • CysLT and LTB-4 are very potent bronchoconstrictors. From what are they derived? (12)
  • Eosinophil CysLT causes a second wave of smooth muscle constriction after the initial allergic event in allergic asthma. What is this known as? (4, 5)
  • From what are the key lipid mediators in inflammation derived? (11, 4)
  • When an allergen comes into contact with an allergic airway, what happens to the FEV1? (5, 8)
  • When eosinophil CysLT is released, which cells are stimulated to produce more mucus? (6, 5)
  • Where do B cells mature? (4, 6)
  • WHere is FC-epsilon-R1 expressed? (4, 5)
  • Which enzyme converts Arachidonic Acid into Prostaglandins? (5, 9)

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