IB standard Biology: cells (cell cycle)

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What is Chromatin?
uncoiled DNA, associated with proteins
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What is a Chromosome?
supercoiled, condensed DNA
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What is a sister chromatid?
one half of a chromosome, made up of 1 short arm and 1 long arm
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What connects the 2 sister chromatids?
the centromere
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What is the anagram to help remember the cell cycle?
shIPMATe
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How long is the interphase?
Longest part of the cell cycle
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What are the phases of interphase? (longest stage)
G, S, G2
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What happens in the G phase?
The cell grows in size, cellular contents (other then Chromosomes) replicated, protein synthesis, checkpoint 1 (to check all DNA ready for synthesis)
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What is the G0 phase?
The cell 'quits' the cell cycle, doesn't divide or replicate and dies at the end of its life
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What happens in the S phase?
DNA synthesised (replicated), so that each chromosome now has an identical sister chromatid (connected to them by centromere)
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What happens in the G2 phase?
more proteins synthesised, grows in size, checkpoint 2 (check that new DNA is error free after replication), spindle microtubules made
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Name 4 processes that involve mitosis
tissue repair, asexual reproduction, replacement of cells, embryonic development
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What are the 4 stages of mitosis?
Prophase, Metaphase, Anaphase, Telophase
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What happens in Prophase?
Chromatin condenses by supercoiling, nuclear envelope breaks down and disintegrates, centrioles move to opposite poles (and form microtubule spindle fibres)
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What happens in Metaphase?
Microtubule spindle fibres connect to the centrosome of each chromosomes, then the fibres shorten and contract so the chromosomes line up along the equator of the cell
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What happens in the Anaphase?
The sister chromatids split into individual chromosomes, and are pulled to opposite poles of the cell by the still connected spindle fibres
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What happens in the Telophase?
The spindle fibres dissolve, chromosomes de-condense (back into chromatin), and nuclear membranes reform around each set of chromosomes (so there are 2 daughter nuclei)
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What does a microscope image of the Prophase look like?
Grainy circle in the middle of the cell (which is the condensing chromatin)
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What does a microscope image of the Metaphase look like?
Chromosomes are lined up along the middle
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What does a microscope image of the Anaphase look like?
bananas / fingers being pulled apart
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What does a microscope image of the Telophase look like?
2 dark circles (each individual nuclei) at each end of the cell
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What happens in Cytokinesis?
The (double-nucleated) cell splits into 2 daughter cells
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How does Cytokinesis happen in animal cells?
the plasma membrane elongates and pinches inwards
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How does Cytokinesis happen in plant cells?
A firm plate is formed in between the 2 daughter cells
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How would you calculate mitotic index?
number of cells in mitosis/total number of cells or time spent in mitosis/time for 1 cell cycle
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What is a Mutagen?
An agent (biological/chemcial/radioactive) that causes genetic mutations
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What is an Oncogene?
A gene which (in certain circumstances) can transform into a tumor cell
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What is a primary tumor?
A tumor that forms at the anatomical site where the tutor started developing
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What is Metastasis?
Tumor cells being transported in the bloodstream to other parts of the body, causing secondary tumors
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Tumors are the result of ...
uncontrolled cell division
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why are tumors so dangerous?
they don't differentiate into normal cells, and develop their own blood supply and grow at the expense of surrounding tissue
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Other cards in this set

Card 2

Front

What is a Chromosome?

Back

supercoiled, condensed DNA

Card 3

Front

What is a sister chromatid?

Back

Preview of the front of card 3

Card 4

Front

What connects the 2 sister chromatids?

Back

Preview of the front of card 4

Card 5

Front

What is the anagram to help remember the cell cycle?

Back

Preview of the front of card 5
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