the base change results in the formation of a stop codon. production of polypeptide stopped prematurely & final protein would almost certainly be different & unable to perform normal function. (substitution mutation)
1 of 7
Mis-sense mutation
base change results in a different amino acid being coded for. Significance is dependant on role of single amino acid, for example in terms of tertiary structure bonding as protein may differ in shape.
2 of 7
Silent mutation
substituted base codes for same amino acid due to degenerate nature of genetic code.
3 of 7
Mutation by deletion
nucleotide is lost from DNA sequence. Usually, the new sequence of amino acids s entirely different as bases are read in triplets. losing one base causes all the bases to shift along one, so every triplet changes.
4 of 7
Mutagenic Agents
outside factors that increase basic mutation rate (i.e high energy radiation & chemicals)
5 of 7
Proto-ocnogenes
genes that stimulate cell division
6 of 7
Tumour suppressor genes
genes that slow cell division
7 of 7
Other cards in this set
Card 2
Front
base change results in a different amino acid being coded for. Significance is dependant on role of single amino acid, for example in terms of tertiary structure bonding as protein may differ in shape.
Back
Mis-sense mutation
Card 3
Front
substituted base codes for same amino acid due to degenerate nature of genetic code.
Back
Card 4
Front
nucleotide is lost from DNA sequence. Usually, the new sequence of amino acids s entirely different as bases are read in triplets. losing one base causes all the bases to shift along one, so every triplet changes.
Back
Card 5
Front
outside factors that increase basic mutation rate (i.e high energy radiation & chemicals)
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