Other questions in this quiz

2. CYP2D6 substrates have?

  • basic nitrogen, ionised at physiological pH, hydrophobic region
  • hydrophilic with sulphur centres
  • strong hydrogen bond forming potential or ion pair formation
  • hydrophobic interactions

3. CYP2C9 substrates include:

  • verapamil, lidocaine, cyclosporin
  • omeprazole, clopidogrel
  • ibuprofen, s-warfarin, tienllic acid
  • debrisoquine, amitriptyline, codeine

4. CYP2D6 substrates include:

  • verapamil, lidocaine, cyclosporin
  • omeprazole, clopidogrel
  • debrisoquine, amitriptyline, codeine
  • ibuprofen, s-warfarin, tienllic acid

5. CYP26:

  • all drug metabolism
  • fatty acid oxidation
  • retinoid acid oxidation
  • steroid biosynthesis (oestrogen)

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