clincial biochem 2- u and e

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  • Created by: anna888
  • Created on: 30-01-23 15:50
what is normal gfr
120ml/l
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what is normal urine output
1-2l in 24hrs
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why is crcl used as measurement of kidney function
100% of creatine cleared from kidney, used as proxy for gfr
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where is creatinine produced
muscle breakdown product
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whats cockcroft gault equ
crcl= (140-age) x weight x (1.23male/1.04female) divided by srcr
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what are the parameters
50-20 is mild impairment, 20-10 is moderate less than 10 is severe
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stage 5 kideny failure gfr?
less than 15
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what is normal urea levels, what is main excretion in urea, what does high urea mean
2.5-6.6mmol, nitrogen, dehydration
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what are normal potassium serum levels
3.5-5.3mmol/l
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roles and location of potassium
found mainly intracellular but largerly availbale for exchange, influences membrane potential, obtaind from diet and kidney reabsorbtion
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what are hypokalaemia levels and what are the clincial manifestations of this
less than 3.5mmol/l, ecg chnages, drowsy,cramps
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what are hyperkalaemia levels and clincal manifestations
greater than 6.5mmol/l, ecg changes, ventricular fibrlation, death
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describe soudium uses and where is it found
influences membrane potentials, less available for exchange than potassium, rest stored in bones
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what are hyponatraemia levels and what is it caused by and manifestations
less than 135mmol/l, excess of water compared to na and kdiney has impaired abaility to excrete dilute urine, confusion, seizures, cerebral oedema
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what are hypernatraemia levels, what is it caused by and what are the clinical manifesations
greater than 145mmol/l. excess of na compared to water, impaired thirst mechansims eg via drugs
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what is normal protien loss levels
less than 150 mg/day
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what is normal urine output

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1-2l in 24hrs

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why is crcl used as measurement of kidney function

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Card 4

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where is creatinine produced

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whats cockcroft gault equ

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