Cell biology 10S.2 0.0 / 5 ? BiologyMechanisms and therapy of cancerUniversityAll boards Created by: Jasmine FinchCreated on: 25-05-20 09:20 caretakers tumor suppressors involved in DNA damage repair 1 of 9 Gatekeepers tumor suppressors involved in cell death and cell cycle arrest 2 of 9 Is p53 a caretaker or gatekeeper? gatekeeper 3 of 9 Why do elephants not get cancer? they have 12 copies of the tumor suppressor TP53 4 of 9 RB is a tumor suppressor, germline mutations can cause retinoblastoma 5 of 9 RB regulates the G1/S checkpoint of the cell cycle 6 of 9 BRCA1 and BRCA2 are caretakers and tumor supressors (involved in double stand break) 7 of 9 what famous celebrity had BRCA1/2? Angelina Jolie 8 of 9 why does angiogensis occur in tumor cells? occurs when oxygen tension is low 9 of 9
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