Biological Therapies for Schizophrenia 5.0 / 5 based on 1 rating ? PsychologySchizophreniaA2/A-levelAQA Created by: AmyTheDolphinCreated on: 30-10-17 08:35 Why might antipsychotics be delivered via an injection or syrup? When a paitent refuses to take the medication themselves and dosage needs to be carefully monitored. 1 of 30 Why do paitents not take medication? Paranoia of what the drug might do to them, dislike the sedative effects, forget to take them due to poor memory. 2 of 30 Typical antipsychotics can also be referred to as...? First generation 3 of 30 Atypical antipsychotics can also be referred to as...? Second generation 4 of 30 What is an example of a typical antipsychotic? Chlorpromazine 5 of 30 What is an example of an atypical antipsychotic? Clozapine 6 of 30 How does Chlorpromazine work? They are dopamine antagonists. The drug binds to dopamine receptors but does not stimulate them, thus blocking their action 7 of 30 How does Clozapine work? They bind to dopamine receptors (especially D2) but are though to act on glutamate and serotonin receptors also 8 of 30 Why might Clozapine be prescribed? Because of its mood-enhancing effects, it can be helpful if someone is at high risk of committing suicide 9 of 30 What is the rate for attempted suicide in people with schizophrenia? 30-50% 10 of 30 What is the advantage of Risperidone over Clozapine? Decreased side effects 11 of 30 What is the maximum daily dosage for Chlorpormazine? 1000 mg, but usually reduced to 400mg 12 of 30 What is the maximum daily dosage for Clozapine? 300-450mg 13 of 30 What is the maximum daily dosage for Risperidone? 12mg 14 of 30 How are injections of antipsychotics effective for paitents who forget or refuse to take medication? It has a slow releasing effect so paitents only need to be administered it every 2-4 weeks 15 of 30 What is the advantage of administering Chlorpromazine as a syrup? It's fast absorbing and therefore allows its sedative properties to come into effect quickly when paitents are anxious 16 of 30 What is the name of the dangerous blood disease Chlorpromazine can cause? Agranulocytosis 17 of 30 What is a severe side effect of typical antipsychotics Tardive Dyskinesia 18 of 30 Why does Neuroleptic Malignant Syndrome (NMS) occur? Drug blocks the dopamine receptors in the hypothalamus, which is associated with the regulation of several body symptoms. 19 of 30 The symptoms of NMS are? High temperature, delirium and coma 20 of 30 What is the rate of non-compliance for taking antipsychotics? 40% 21 of 30 Why does Clozapine have the lowest non-compliance rate (5%)? Administration is strictly monitored 22 of 30 How likely is developing NMS with typical antipsychotics? 0.1%-2% 23 of 30 How likely is developing Tardive dyskinesia with typical antipsychotics? 32% 24 of 30 How likely is developing Tardive dyskinesia with atypical antipsychotics? 13% 25 of 30 How much weight is gained over 10 weeks with typical antipsychotics? 5kg 26 of 30 How much weight is gained over 10 weeks with atypical antipsychotics? 2-4kg 27 of 30 What is the main issue with treating people with antipsychotics? They don't have a coping mechanism, and so they believe recovery is only possible on medication, and feel helpless when symptoms reoccur. 28 of 30 What is the effect size (according to Leucht et al.) for acute cases of schizophrenia? 0.51 29 of 30 What is the effect size (according to Leucht et al.) for relapse cases of schizophrenia? 0.92 30 of 30
Describe and evaluate family dysfunction as an explanation for schizophrenia 4.5 / 5 based on 3 ratings
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