Biochemistry revision: Signalling

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1. A _____________ is a cell surface transmembrane receptor that works with the help of a G-protein, which binds to the energy rich GTP

  • Receptor tyrosine kinases
  • G protein coupled receptor
  • Ligand gated receptor
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2. The similarity in structure of G proteins across a diverse selection of organisms suggests

  • G proteins evolved very early
  • G proteins were in bacteria, that were eaten by eukaryotes

3. An enzyme that catalyzes the transfer of a phosphate group

  • Kinase
  • Carboxlyase

4. ________ is the detection of a signalling molecule coming from outside the cell, this occurs when the molecule binds to the receptor protein on the cell surface membrane

  • Response
  • Reception
  • Transduction

5. The ability for a single ligand binding event to trigger so many pathways is a key difference between receptor tyrosine kinases and ___________

  • G protein coupled receptors
  • Ion channel receptors

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