6. Generally, there are __ stages of cell signalling
3
30
7. _________ is the binding of the signal molecule changes the receptor protein in some way into a form that can bring about a cellular response
Response
Transduction
Reception
8. Ligand gated iron channels contain a region that acts as a gate, when a ligand binds, the gate opens or closes
True
False
9. Ligand gated iron channels function as tyrosine kinases
False
True
10. ________ is the detection of a signalling molecule coming from outside the cell, this occurs when the molecule binds to the receptor protein on the cell surface membrane
Response
Reception
Transduction
11. RTK: The part of the receptor protein that extends into the _________ functions as a tyrosine kinase
Cytoplasm
Extracellular matrix
12. A secreting cell acts on nearby target cells by discharging molecules of a local regulator into the extracellular fluid
Synaptic signalling
Paracrine (local)
Endocrine signalling (long distance)
13. A nerve cell releases neurotransmitter molecules into a synapse, stimulating the target cell
Synaptic signalling (local)
Endocrine signalling (long distance)
14. An enzyme that catalyzes the transfer of a phosphate group
Kinase
Carboxlyase
15. A tyrosine kinase is an enzyme that catalyzes the transfer of a _________ group from ATP to the amino acid tyrosine on a substrate protein
Manganese
Phosphate
Iron
16. The ability for a single ligand binding event to trigger so many pathways is a key difference between receptor tyrosine kinases and ___________
