B13.6 - Gene Expression & Mutation 0.0 / 5 ? BiologyDNA and inheritanceGCSEAQA Created by: fuzz.yCreated on: 22-10-17 12:39 What do we mean by "Gene Expression"? if it is used to make a protein 1 of 18 What controls Gene Expression? Non-coding parts of DNA 2 of 18 What do these parts of DNA do? Non-coding parts of DNA switch genes on and off 3 of 18 How do they affect Gene expression? They control the genes so they control the protein made 4 of 18 Define Mutation? change in the sequence of DNA bases 5 of 18 What are some factors that can increase Mutations? exposure to radiation or some substances 6 of 18 What can Mutations do to a gene? change the protein that the gene codes for 7 of 18 Do Mutations have big effects? Most have very little/no effect 8 of 18 Sometimes the effect if serious. What can this lead to? (protein) Alter the gene; Alter the protein shape; so change the function of the protein 9 of 18 What do Mutations mean for enzymes? they lose their active site and so the substrate no longer fits into the enzyme 10 of 18 If there are mutation in the Non-coding part of DNA, what happens? The gene expression is affected 11 of 18 List the 3 types of Mutation? 1) Insertions 2) Deletions 3) Substitutions 12 of 18 What is Insertion? new base is inserted into DNA base sequence 13 of 18 What can this change? (3 bases code for an amino acid) the amino acid 14 of 18 Does this have a knock on effect? Yes - insertions can change more than one amino acid 15 of 18 What is Deletions? random base is deleted from the DNA base sequence 16 of 18 Does this have a knock on effect? Yes - further down the sequence 17 of 18 What is Substitution? random base in the DNA base sequence is changed to a different base 18 of 18
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