Actin Binding Proteins

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Profilin
Maintains actin monomer pool. Promotes nucleotide exchange
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Arp 2/3
Nucleates actin filaments as side branches from existing filaments
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Capping Protein
Binds to growing filaments and prevents further growth.
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ADF/Cofilin
Promotes filament disassembly
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Ena/Vasp
Promotes filament elongation
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Fascin
Cross links actin filaments into parallel bundles in filopodia
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Formins
Nucleate actin filaments and promote filament growth
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Myosin II
Forms contractile cables in combination with actin filaments
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Tropomyosin
Stabilises actin filaments
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Alpha-actinin
Cross links actin filaments in contractile actomyosin cables
10 of 11
Filamin
Cross links filaments in disordered actin networks
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Other cards in this set

Card 2

Front

Nucleates actin filaments as side branches from existing filaments

Back

Arp 2/3

Card 3

Front

Binds to growing filaments and prevents further growth.

Back

Preview of the back of card 3

Card 4

Front

Promotes filament disassembly

Back

Preview of the back of card 4

Card 5

Front

Promotes filament elongation

Back

Preview of the back of card 5
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