Proteins in the ECM

?
RhoA
Triggers actin nucleation (?), Activates myosin contractility during retraction
1 of 19
ROCK1
Activates contractility
2 of 19
RhoE
Downregulates ROCK1
3 of 19
KIAA0861
Possible activator of RhoA
4 of 19
Protein 4.1
Might form part of an erythrocytic cytoskeleton under the growing bleb membrane
5 of 19
Myosin I
Motor protein in contractility
6 of 19
Src
Controls RhoA (?)
7 of 19
Ezrin
Tethers the actin cortex to the membrane
8 of 19
Moesin
Tethers the actin cortex to the membrane
9 of 19
Actin
Main component of the cortical network
10 of 19
Alpha-Actin
Bundles actin
11 of 19
Coronin
Bundles actin
12 of 19
Fimbrin
Bundles actin
13 of 19
Cortactin
Bundles actin
14 of 19
Tropomyosin
Controls myosin contraction
15 of 19
Tropomodulin
Caps actin-filament pointed ends
16 of 19
Myosin II
Contracts the cortex during bleb retaction
17 of 19
Anillin
Coordinates myosin II and actin contractility
18 of 19
Myosin light chain kinase
Activates myosin contractility
19 of 19

Other cards in this set

Card 2

Front

Activates contractility

Back

ROCK1

Card 3

Front

Downregulates ROCK1

Back

Preview of the back of card 3

Card 4

Front

Possible activator of RhoA

Back

Preview of the back of card 4

Card 5

Front

Might form part of an erythrocytic cytoskeleton under the growing bleb membrane

Back

Preview of the back of card 5
View more cards

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