Polypeptide synthesis - translation

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Synthesising a polypeptide:

  • A ribosome becomes attached to the starting codon at one end of the mRNA molecule
  • the tRNA molecule with the complementary anitcodon sequence moves to the ribosome and pairs up with the codon on the mRNA. This tRNA carries a specific amino acid
  • A tRNA molecule woth a complemantary anticodon pairs with the next codon on the mRNA. This tRNA molecule carries another amino acid
  • The two amino acids on the tRNA are joined by a peptide bond using an enzyme (peptidyl transferase) and ATP which is hydrolysed to provide the required energy
  • The ribosome moves on to the third codon in the sequence on the mRNA, thereby linking

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