Animals are often used in addition in addition studies, which involve getting the animals addicted to something and then trying to get them un-addicted.
As a result of this aniamls experience pain and suffering, but it's done so that humans can safely take psychoactive drugs and have happy lives without hurting any members of the public.
Similariliy, Selye carried out unethical research on rats (cutting into their spine, exposing them to extreme temperatures etc...) which helped us understand how stress effects the heath of humans.
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