1) With reversible reactions some of the products are always reacting together to turn back into reactants. So the yield will be lower.
2) When you filter a liquid to remove a solid, you always lose a bit of liquid or a bit of solid. so, some of the product may be lost when it's separated from the reaction mixture.
3) Sometimes there can be other unexpected reactions happening. these will use up the reactants. This means there's not as much reactant to make the product you want.
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