APPLIED LIFE SCIENCE REVISION

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KEY DIAGNOSTIC FACTORS OF UTI

DYSURIA: pain or burning when passing urineEx

NEW NOCTURIA: passing urine more often at night

CLOUDY URINE: urine cloudy to the naked eye

FEVER: the absence of same does not exclude a UTI

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OTHER COMMON SIGNS AND SYMPTOMS

  • Urgency
  • Visible haematuria
  • Frequency
  • Suprapubic pain or tenderness
  • New incontinence
  • New or worsening delerium
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STRONG RISK FACTORS

  • Sexual activity
  • Spermicide use
  • Post menopause
  • Positive family history of UTI
  • History of recurrent UTI
  • Presence of foreign body
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WEAK RISK FACTORS

  • Insulin treated diabetes
  • Recent antibiotics
  • Poor bladder emptying
  • Increasing age
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CLINICAL MANIFESTATIONS- DYSURIA

  • Results from irritation. of the bladder trigone or urethra
  • Inflammation or stricture of the urethra causes difficultyies starting urination and burning on urination
  • Urine comes in contact with inflamed mucosa- nociceptors and sensory nerves stimulated which causes pain along with burning, stinging or itching.
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CLINICAL MANIFESTATIONS- FREQUENCY, URGENCY AND CO

  • Reduced bladder capacity due to inflammatory oedema causeing decreased compliance and pain due to bladder distention. 
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CLINICAL MANIFESTATIONS- CLOUDY URINE

  • Typically comes from discharge of either pus or blood into the urinary tract- potentially also be a build up of white blood cells as the body tries to eliminate invading bacteria.
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CLINICAL MANIFESTATIONS- NO FEVER

  • If fever was present: normally the hypothalamic thermoregulatory centre maintains internal temperature between 37 and 38 degrees celcius.
  • Fever results when something raises the hypothalamic set point, triggering vasoconstriction and shunting of blood from the periphery to decrease heat loss; sometimes shivering, which increases heat production, is reduced.
  • These processes continue until the temperature of the blood bathing the hypothalamus reaches the new set point.
  • Resetting the hypothalamic set point downward initiates heat loss through sweating.
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CLINICAL MANIFESTATIONS- NO FLANK PAIN

  • If present: caused by distention of the ureter or renal pelvis or distention of the renal capsule, due to inflammatory response following infection.
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