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1. Naked mole rats show various adaptations to their particular environment Given an example of
these adaptations exhibited by these animals.
2. Give two examples of features that help thermoregulation in most mammals that are reduced or
absent in naked mole rats and explain how each operates to help achieve thermoregulation.
3. Give one advantage and one disadvantage in being poikilothermic in comparison to homeothermy.
4. The non-reproductive individuals in eusocial animals do not directly transfer their genes to
offspring. In spite of this there must still be a genetic advantage in being eusocial suggest what this
5. What evidence would scientists look for when searching for evidence of heart disease in naked
6. Suggest how extra molecules attaching to proteins might affect their structure and function.
7. Suggest what processes would be altered by the cancer causing genes.
8. Describe the techniques that would be used to insert the cancer causing genes into the cells of the
9. How might the immune system of immune compromised mice differ from normal mice?
10. Name the process by which cells replicate (p14) and describe the events that take place in the
main events of this process.
11. Explain how transcription factors bring about expression of a gene (p24)
12. Describe the procedures of a potential new anti-cancer therapy would have to go through
before it could be licensed as a drug.
13. Explain how impulses would be transmitted from the pain receptors of a rodent to its central
14. What is the sequence of neurones impulses would pass through, to result in withdrawing a hand
from a hot stove?
15. Describe the responses that humans would show if they were breathing air with 5% carbon
dioxide, and explain how these responses are brought about.
16. A brain deprived of oxygen will lead to a brain deprived of ATP/energy. Describe the role of
oxygen in the production of ATP.
17. Explain how populations of naked mole rats have evolved to be resistant to hypoxia.
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Use of modern scanning techniques has transformed our understanding of the localisation of
function in the brain. Describe how FMRI can be used to study brain function and compare this with
early techniques that were used to investigate brain function.
19. From p47 why are the new prosthetics being developed at UCL less likely to damage tissues, and
why is there a problem that must be overcome with these prosthetics.