Unipolar depression

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  • Created by: isobel
  • Created on: 15-06-13 09:52
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  • Unipolar depression
    • symptoms
      • the Dsm lists 9 symptoms and 5 or more must be present during thesame 2 week period and must include either a depressed mood or loss of interest
      • -extreme lethargy         -disturbed sleep             -feelings of despair and hopelessness                   -loss of interest in usual activities
    • Explanation- Monoamine hypothesis
      • A group of transmitters called monoamines, which include noradrenaline, dopamine and seratonin, exist in lower levels in the brains of depressed patients.
      • without the correct levels of seratonin you will feel anxious and will have a lack of energy and sleep disturbances
      • without thecorrect levels of dopamine you will lack motivation and feel despair and wont beable to stimulate your reward pathway, so wontfeel pleasure.
      • ifyou lack noradrenaline you will lack motivation and concentration and would struggle to get over things.
    • Evaluation of Monoamine hypothesis
      • Antidepressants are an effective treatment and work by raising levels of monoamines
      • however antidepressants dont work for everyone suggesting there must be another cause
      • Bunney et al- Urinary levels of norepinephrine decreased as patients became depressed
        • however using urine doesnt give a direct reflection of levels of neurotransmitters in the brain, could come from anywhere in the body.
      • Delgado et al- used a special diet to reduce seratonin levels in remitted depresed patients and found that 67% of patients experienced a return of symptoms
      • comparison-cognitive approach states its faulty thinking patterns not neurotransmitters

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