Schizophrenia: The Dopamine Hypothesis

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  • Created by: Bham369
  • Created on: 06-12-17 10:18
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  • The Dopamine Hypthesis
    • Usefulness
      • Drugs can be used
        • They can have unwanted side effects
    • Scientific
      • Brain Scans can be used
      • Drug Trials can be done
        • unwanted/unexpected side effects
      • Empirical Trials
    • Reductionist
      • Ignores the nurture side of the debate
    • Studies
      • Griffeth et al
        • Gave a group of non-schizophrenic a drug to raise dopamine levels (L-Dopa)
          • The participants became paranoid, cold, detached and unemotional
            • Same symptoms of sz patients
              • Links high dopamine levels to the development of sz
      • Cole et al
        • Gave anti-psychotics to sz patients
          • The drug was designed to block D2 (dopamine 2) receptors in the brain
            • 75% of the patients condition improved
              • Shows that too much activity in the D2 receptor can lead to the development of sz
              • Not 100% so something else must be involved in the development of sz

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