Rhinovirus
- Created by: Emilyburkee
- Created on: 01-01-23 11:28
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- Rhinovirus
- Virology
- Non-enveloped positive-sense ssRNA
- 3 groups/species of Rhinovirus: A, B & C
- Rhinovirus A & B predominantly use ICAM-1 as a receptor (sometimes LDL-R)RV-C uses CDHR3
- Transmitted through aerosols/microdroplets and fomites
- prefer 32oC
- history & epi
- Primary cause of the ‘common cold’Responsible for over 50% of URTI
- Symptoms include: runny nose, sneezing, coughing, sore throat, headache, fatigue, aches
- Symptoms apparent. ~2 days post infectionCommonly asymptomatic
- immunity
- type 1 and 3 by a role
- simalr cytokine production
- disrupts junctions between cells
- Immune response to infection = pro-inflammitory cytokines and increased airway responsivness
- Virology
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