Mutations
- Created by: jessicawarren
- Created on: 18-05-16 16:50
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- Mutations
- Changes to DNA
- Involve change in DNA base sequence of chromosomes
- Substitution- one base substituted with another
- Deletion- one base is deleted
- Order of DNA bases determines order of amino acids in particular protein
- If a mutation occurs, sequence of amino acid could be altered and therefore the protein
- Order of amino acids
- Degenerate nature of genetic code means some amino acids are coded for by more than one triplet
- Not all substitutions will change amino acid sequence- some will still code for same amino acid
- Deletions always lead to change in amino acid
- Deletion changes number of bases present which will cause a shift in all base triplets after it
- Mutagenic agents
- Increase rate of mutation
- Mutations occur spontaneously e.g. when DNA misread during replication
- UV radiation, ionising radiation, some chemicals and some viruses are mutagenic agents
- Changes to DNA
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