Cystic fibrosis is caused by a mutation in the CF gene, the length of DNA that codes for the CFTR protein. The CF gene occurs in two alternative forms or alleles. First, there is the normal allele which codes for the functioning for the CFTR protein. Secondly there is the mutated allele which produces a non-functional protein.
The alleles that a person has makes up their genotype. FF, and ff, show a homozygous genotype for the CF gene - there are two identical copies of the allele. Ff is heterozygous for the CF gene.
The characteristic caused by the genotype, is the phenotype.
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