Biology - Lecture 2 (Brain Imaging)

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  • Lecture 2 - Brain imaging
    • Scans
      • CT scans (x-rays): moderately invasive, inexpensive, low spatial resolution, used clinically but not for  neuropsychology
      • MRI: completely non-invasive, uses radio frequencies, high spatial resolution, first-choice if you need a structural image.
      • PET scan: moderately invasive, radioactivity is introduced into the body, you can measure neural activity (blood flow in the brain), high spatial resolution, v expensive.
      • fMRI: non-invasive, indirectly measures blood flow and shows up as ‘activity’, measures slow processes, high spatial resolution, medium expensive.
    • History of detecting brain  function
      • Angelo Mosso (1881) = balancing board, intellectual avidity = head end tips
      • Paul Broca (1897) = measured temperature with gages all around the brain, after intellectual task frontal lobes were hotter than occipital   
      • John Belleiviaw & Thomas Brady (1991) = first functional MRI images

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