immunity- the cells
- Created by: vezting
- Created on: 03-04-16 14:39
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- immunity- the cells
- Phagocytes
- neutrophils
- multilobed nucleus
- made in the bone marrow
- travel in blood, then squeez out into tissue fluid
- neutrophils are short lived and may collect in an area of infection to form puss
- macrophages
- larger cells, yet still mad ein bone marrow
- travel in the b lood as monocytes, settle in organs, mostly lymph node,
- in lymph node they become macrophages
- trhey release cytokines that stimulate B cells to differentiate
- 1: when pathogen invades body, it is recognised as forgein and macrophages initiate the immune response
- 2:antibodies in the blood stream attach to the foreign antegic (complementary)
- 3: neutrophils have membrane bound proteins (receptors) that attach to the antibody already attached to antigen
- 4: neutrophils engluf the pathogen by folding in the membrane, this creates a phagosome vacuole
- 5: lysosomes fuse with phagosome and inject lysins (enzymes) which digest the bacterium
- the end products are harmless nutrients that are absorbed into cytoplasm
- infected cells release histamine, this makes capillaries more leaky
- leaky capillaries means more fluid leaves, and enters lympahtic system
- fluid in the lymphatic system leads pathogens towards lymph nodes
- neutrophils
- lymphocytes and the response
- Phagocytes
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