Biology burt

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  • Bio mock blurt
    • Biological moles
      • polymers of glucose
        • starch
          • amylopectin
            • -same as amylose but has more 1-6 meaning it has a branched structure
          • amylose
            • -alpha glucose, 1-4 glycosidic       bonds.             -helical
        • glycogen
          • lots of 1-6 meaning it is highly branched
        • cellulose
          • beta glucose, everyother mole= inverted giving it a straight and rigid structure
          • beta pleted sheet = h bonds between the layers = strong
        • benidicts solution = brick red
          • if non- reducing = hydrolyse  then neutralise
      • Lipids
        • triglycerides
          • x 1 glycerol. x 3 fatty acids
            • saturated = solid at room temp
            • unsaturated = C=C solid
        • phospholipids
          • x1 glycerol. x1 phosphate group x2 fatty acids
            • hydrophilic head, hydrophobic tail
        • insoluble in water + long store e
        • emulsion test = ethanol water shake
        • ester bomnd
      • proteins
        • primary structure
          • the order of amino acids
        • secondary structure
          • simple folding in sections of the polypeptide due to hydrogen bonding
        • tertiary structure
          • 3D folding due to interactions between R-groups
        • quaternary structure
          • multiple polypeptide chains
        • bueriet test - blue to violt
    • structure and replication of prokaryotes
      • no membrane bound organelles no nucleus cell wall from meurin flagellum  70s ribosomes
        • no histones capsule
      • binary fission
        • DNA rebelicate and bind to membrane, membrane pinches and cytoplams splits
      • virues
        • tiny, acellular non living
        • trverse transcriptase  attachment proteins capsule rna lipid envelope
        • binds to membrane releses enzymes and rna
          • reverse transcriptase RNA-DNA and intergrase incorporates it in    sytheisi of viral proteins
    • Genetic code and protein synthesis
      • codon = 3 bases
      • histones
      • anti parrallel, stable and helical
      • degenerate = multiple codons can code for the same amino acid
      • non-overlapping and universal
      • introns = non-coding and exons = coding
      • allele = different form of same gene
      • gene= sectio of DNA which codes for a specific protien
      • transcription
        • DNA helicase = breaks h bonds between complementary bases
          • free RNA nucleotides join condensed by RNA polymerase
            • introns are spliced out
      • translation
        • 2 codons bind to ribosome - START codon
          • tRNA with comp anticodon binds bringing specific amino acid
            • repeats with peptide bonds formed between aa
              • Stop codon = protein folds
    • variation and natural selection
      • genetic diversity = number of different alleles in a given pop
      • mutation
        • deletion and addition = frame shift= non functional protein
        • subsitution= can have 0 effect
        • chromosonal = occur on whole chromosome
          • non disjuntion
      • meosis
        • crossing over= chiasmata forms- parts of chromosomes assosiate and sawp = new combo of genes
        • independent assortment = chromosomes randomly pulled to diff dells
          • diff combos of maternal and paternal
        • random fertilisation
        • second divison chromotids split at centromere
      • natural selection
        • variation = random, could lead to desirable trait
          • increases chance of survival
            • outcompetes
              • reproduces
                • increae in allele frequency
    • immunity and antibodies
      • b cells
        • b cell with complementary tertiary structured antiboys on surface bind to antigen
          • this in combination with the binding of Th cells causes colonal expansion
            • mitosis
              • many plasma b cells which all produce same monocolonal antibody
      • antibodies
        • 4 polypeptides
          • 2 heavy, 2 light chains
          • variable regions and constant region
        • agglutination
          • one antibody binds to multiple antigens
            • prevents antigen from binding
        • neutralisation
          • antibody binds + prevents it from binding
      • vaccinations
        • active artifical immunity
          • pathogen/ antigen intoduced
            • induces primary immune resopnse
              • ready for secondary
    • digestion and absorption
      • proteins
        • endopepdiases = inner peptide bonds
          • exopeptidaes - outer peptide bonds
            • dipeptidases - between 2 amino acids
        • absorption = co or active transport
      • lipids
        • bile salts emulsify= high SA for lipase
        • absorption
          • micelles enter cell and arrive at golgi- triglerides
            • associated with a protein = chylomicrons
              • vesicle to the blood
      • carbs
        • salivary amylase = startch to maltose
          • denatured
            • pancratic amylase  = rest to maltose
              • membrane-bound disaccarides
                • maltose to glucose
        • co-transport
          • NA pumped out actively
            • NA diffuse back in with glucose via carrier protein one with one against GC
              • glucose diffuses out
    • cardiac cycle
      • diastole- relaxation of heart mucles
        • blood flows in as valves open
      • atrial systole
        • atria contract
          • p in a = higher than  vein
          • semi lunar close
      • ventricular systole
        • ventricles contract
          • p in V higher than A so AV closes
            • semilunar opens
              • blood flows out

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