Antenatal Screening
- Created by: georgiasadler
- Created on: 25-02-15 18:11
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- ANTENATAL SCREENING
- BLOOD TESTS
- Iron content
- Mother's blood
- Indicate anaemia
- Mother's blood
- Blood grouping
- ABO
- Rehsus
- Spina bifida
- levels of AFP
- alphafetoprote-in
- levels of AFP
- Iron content
- AMNIOCENT-ESIS
- Small amounts of amniotic fluid drawn from amniotic sac
- Fluid sent to be chemically analysesd
- Skin cell culture
- 16 - 18 weeks of pregnancy
- Foetus detected on ultrasound
- Allows insertion of hollow needle
- Needle penetrates amniotic sac through uterine wall
- No anaesthetic
- Needle penetrates amniotic sac through uterine wall
- Allows insertion of hollow needle
- Increases risk of miscarriage 1%
- Results take 3 - 4 weeks
- Cells have to be grown
- Mainly used to identify chromosomal abnormalities
- CHRONIC VILLUS SAMPLING
- First 12 weeks of pregnancy
- Usually due to family history
- Chronic villi have same genetic make up as foetus
- Can be cultured directly for chromosomal analysis
- Takes 30 minutes
- Hollow cannula
- Access through vagina (endoscope)
- Access through uterus wall
- Ultrasound to locate placenta
- 1 - 2% increase risk of miscarriage, bleeding, or infection
- Downs syndrome
- Sickle cell disorders
- Haemophillia
- Thalassemia
- Muscular dystrophy
- BLOOD TESTS
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