THYROID GLAND 0.0 / 5 ? BiologyTHYROIDUniversityAll boards Created by: StephanieCreated on: 12-05-14 22:00 Where is the thyroid gland located? ventral surf of trachea 1 of 19 what hormones does it secrete? t3 t4 calcitonin 2 of 19 Describe the structure of follicles and colloids each follicle has a protein rich centre colloid. between follicles are c cells which synthesize calcitonin 3 of 19 What is held inside a colloid? Iodide(ionised iodine), Thyroglobulin TG and enzymes req to make hormones 4 of 19 Why are follicular cells close to the capillaries? stimulus to prod hormones is delivered via blood. 5 of 19 Describe the secretion of thyroid hormones see flowchart. 6 of 19 Thyroid hormones are.....philic so.... Receptors... Lipophilic so diffuse into blood. Receptors can be intracellular. 7 of 19 Name 3 carrier proteins Albumin, Trasnthyrethin, Thyroxine binding globulin 8 of 19 T3 is 4x more potent than T4? TRUE. t3 is more active than t4 9 of 19 t3 is produced at 10x greater rate than t4? FALSE. t4 is produced at 10x greater rate than t3. t4 is more abundant form. 10 of 19 Conversion of t4 to t3 is called? Activation 11 of 19 Which is involved in negative feedback? T4 12 of 19 Cellular effects of thyroid hormones include? Increased protein synthesis, cell growth and maturation, increased no of mitochondria and cellular respiration. 13 of 19 Effects on peripheral tissues include? Inc hr and bp, inc rate of O2 and energy consumption, enahnced o2 delivery and stim rbc production. 14 of 19 What do C cells between follicles and basement memb do? produce calcitonin, reg calcium levels in body. 15 of 19 Symptoms of hypothyroidism are feeling hot and weight loss? FALSE. Weight gain and feel cold 16 of 19 What happens in Hashimoto's thyroiditis? Immune system attacks thyroid gland, autoimmune disease. 17 of 19 How hypo is diagnosed? high tsh as problem just with thyroid gland so tsh nowhere for it to act. 18 of 19 How hyper diag? low tsh as neg feedback loop still works but high free t4 as thyroid still hyper secreting hormone 19 of 19
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