THYROID GLAND

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  • Created by: Stephanie
  • Created on: 12-05-14 22:00
Where is the thyroid gland located?
ventral surf of trachea
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what hormones does it secrete?
t3 t4 calcitonin
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Describe the structure of follicles and colloids
each follicle has a protein rich centre colloid. between follicles are c cells which synthesize calcitonin
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What is held inside a colloid?
Iodide(ionised iodine), Thyroglobulin TG and enzymes req to make hormones
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Why are follicular cells close to the capillaries?
stimulus to prod hormones is delivered via blood.
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Describe the secretion of thyroid hormones
see flowchart.
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Thyroid hormones are.....philic so.... Receptors...
Lipophilic so diffuse into blood. Receptors can be intracellular.
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Name 3 carrier proteins
Albumin, Trasnthyrethin, Thyroxine binding globulin
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T3 is 4x more potent than T4?
TRUE. t3 is more active than t4
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t3 is produced at 10x greater rate than t4?
FALSE. t4 is produced at 10x greater rate than t3. t4 is more abundant form.
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Conversion of t4 to t3 is called?
Activation
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Which is involved in negative feedback?
T4
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Cellular effects of thyroid hormones include?
Increased protein synthesis, cell growth and maturation, increased no of mitochondria and cellular respiration.
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Effects on peripheral tissues include?
Inc hr and bp, inc rate of O2 and energy consumption, enahnced o2 delivery and stim rbc production.
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What do C cells between follicles and basement memb do?
produce calcitonin, reg calcium levels in body.
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Symptoms of hypothyroidism are feeling hot and weight loss?
FALSE. Weight gain and feel cold
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What happens in Hashimoto's thyroiditis?
Immune system attacks thyroid gland, autoimmune disease.
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How hypo is diagnosed?
high tsh as problem just with thyroid gland so tsh nowhere for it to act.
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How hyper diag?
low tsh as neg feedback loop still works but high free t4 as thyroid still hyper secreting hormone
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Other cards in this set

Card 2

Front

what hormones does it secrete?

Back

t3 t4 calcitonin

Card 3

Front

Describe the structure of follicles and colloids

Back

Preview of the front of card 3

Card 4

Front

What is held inside a colloid?

Back

Preview of the front of card 4

Card 5

Front

Why are follicular cells close to the capillaries?

Back

Preview of the front of card 5
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