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6. what is parvovirus b19 known as?
- slapped cheek syndrome, fifth disease
- german measles
7. what two ways can CMV be transmitted?
- -saliva/genital secretions, - donated blood, stem cells, solid organs
- -respiratory droplet, - direct contact with vesicle fluid
8. how do the symptoms for congenital CMV infection of the neonate differ to the symptoms of reactivation of latent cmv in immunosuppressed patients?
- congenital- retinitis, deafness, microcephaly, hepatosplenomegaly. -reactivation= retinitis, colitis, pneumonitis
- congenital=retinitis, colitis, pneumonitis. -reactivation=retinitis, deafness, microcephaly, hepatosplenomegaly
9. what disease is epstein barr virus known to cause
- shingles
- chicken pox
- glandular fever/infectious mononucleosis
- cold sores
10. how does infectious mononucleosis present? part of this includes the reason why it is called 'mononucleosis'
- -tonsilitis, fever, lymphadenopathy (affects lymph nodes), hepatosplenomegaly.-get atypical lymphocytes on the blood film that looks like monocytes
- -retinitis, deafness, microcephaly, hepatosplenomegaly in the neonate
11. how many stages of the virus life cycle are there?
12. what is a virus
- a simple micro-organism
- a complex micro-organism
13. how does the latency for epstein barr virus to cytomegalovirus
- ebv= in b cells, cytomegalovirus=in myeloid progenitors/monocytes/dendritic cells
- ebv= in myeloid progenitors/ monocytes/ dendritic cells, cytomegalovirus= in b cells
- ebv=in dorsal root ganglion of whole CNS, cytomegalovirus= in sensory nerve ganglia
- ebv= in sensory nerve ganglia, cytomegalovirus= in dorsal root ganglion of whole CNS