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6. what is parvovirus b19 known as?

  • slapped cheek syndrome, fifth disease
  • german measles

7. what two ways can CMV be transmitted?

  • -saliva/genital secretions, - donated blood, stem cells, solid organs
  • -respiratory droplet, - direct contact with vesicle fluid

8. how do the symptoms for congenital CMV infection of the neonate differ to the symptoms of reactivation of latent cmv in immunosuppressed patients?

  • congenital- retinitis, deafness, microcephaly, hepatosplenomegaly. -reactivation= retinitis, colitis, pneumonitis
  • congenital=retinitis, colitis, pneumonitis. -reactivation=retinitis, deafness, microcephaly, hepatosplenomegaly

9. what disease is epstein barr virus known to cause

  • shingles
  • chicken pox
  • glandular fever/infectious mononucleosis
  • cold sores

10. how does infectious mononucleosis present? part of this includes the reason why it is called 'mononucleosis'

  • -tonsilitis, fever, lymphadenopathy (affects lymph nodes), hepatosplenomegaly.-get atypical lymphocytes on the blood film that looks like monocytes
  • -retinitis, deafness, microcephaly, hepatosplenomegaly in the neonate

11. how many stages of the virus life cycle are there?

  • 6
  • 5
  • 4

12. what is a virus

  • a simple micro-organism
  • a complex micro-organism

13. how does the latency for epstein barr virus to cytomegalovirus

  • ebv= in b cells, cytomegalovirus=in myeloid progenitors/monocytes/dendritic cells
  • ebv= in myeloid progenitors/ monocytes/ dendritic cells, cytomegalovirus= in b cells
  • ebv=in dorsal root ganglion of whole CNS, cytomegalovirus= in sensory nerve ganglia
  • ebv= in sensory nerve ganglia, cytomegalovirus= in dorsal root ganglion of whole CNS