The Digestive System

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Processing food: Organic molecules
Too large to be absorbed and must be broken down by digestion and absorbed in the gut
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Processing food: The gut
Digestion and absorption take place here in a long, hollow, muscular tube
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Processing food: Food passing through the gut
Food is processed as it passes along the regions of the gut
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Processing food: How food moves along the gut
Food is propelled along by peristalsis
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Peristalsis
Wave like contractions that happen in the oesophagus, stomach and intestines that act to propel food along
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Functions of the gut: ingestion
Taking in of food in through the mouth
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Functions of the gut: digestion - mechanical
Cutting or crushing action of the teeth, also rhythmical contractions of the gut wall. Increases surface are for enzymes to act on
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Functions of the gut: digestion - chemical
Achieved through the secretion of digestive enzymes
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Functions of the gut: absorption
Passage of digested food through the gut wall into the blood
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Functions of the gut: egestion
Elimination from the body of food that cannot be digested
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Mouth
Mechanical digestion through action of teeth. Salivary glands release enzymes to start chemical digestion
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Oesophagus
Moves bolus of food from mouth to stomach by a series of rhythmic contractions called peristalsis
Several cells thick and protects the underlying tissues from damage when swallowing
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Stomach
Mechanical digestion of food - rugae help (ridges). Gastric glands secrete hydrochloric acid and enzymes (chemical digestion)
Muscle layer is thick (3 different layers) to provide power to contract and relax
Lots of mucus produced
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Pancreas
Produces pancreatic juice containing enzymes
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Liver
Produces bile which helps emulsify fats and neutralise stomach acid
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Duodenum
First part of the small intestine receiving food from the stomach and secretions from liver and pancreas
Villi (microscopic infolds) - increasing surface area
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Ileum
Part of the small intestine which is responsible for the absorption of digested food
Villi (microscopic infolds) - increasing surface area
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Large intestine - 4 parts
Divided into caecum, appendix, colon and rectum
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Colon
Absorbs water, mineral, salts and vitamins (vitamin K and folic acid secreted by microbes in the gut)
Large number of mucous crypts to secrete mucus
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Tissue layers of the gut wall: outer serosa
Layer of tough connective tissue, protects the wall of the gut, reduces friction from the other organs in the abdomen as the gut moves during the digestive process
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Tissue layers of the gut wall: thick muscle layers
Muscle layer consists of 2 layers of muscle running in opposite directions (inner circular muscle and outer longitudinal muscle), these muscles cause peristalsis
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Tissue layers of the gut wall: submucosa
Consists of connective tissue containing blood and lymph vessels to take away absorbed food products, as well as nerves that coordinate the muscular contractions in peristalsis
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Tissue layers of the gut wall: mucosa
Innermost layer and lines the walls of the gut. Secretes mucus which lubricates and protects the mucosa. In some regions of the gut, this secretes digestive juices, in others it absorbs digested food
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Endopeptidase
Catalyses the hydrolysis of some interior peptide bonds of a protein molecule
E.g. pepsin, trypsin & chymotrypsin
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Exopeptidase
Catalyses the hydrolysis of a peptide bond linking the end amino acid in a peptide chain
E.g. carboxypeptidases & aminopeptidases
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Carbohydrate --> enzymes, pH, substrate & products: mouth
Amylase, pH 7, Starch & Maltose
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Carbohydrate --> enzymes, pH, substrate & products: duodenum
Amylase, pH 7, Starch & Maltose
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Carbohydrate --> enzymes, pH, substrate & products: ileum
Lactase/Maltase/Sucrase, pH 8.5, Lactose/Maltose/Sucrose, Galactose/Glucose/Fructose
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Protein --> enzymes, pH, substrate & products: stomach
Pepsin/Protease/Endopeptidase, pH 2, Proteins & Gastric juice/Polypeptides
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Protein --> enzymes, pH, substrate & products: duodenum
Trypsin/Protease/Endopeptidase, pH 7, Proteins & Peptides/Polypeptides
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Protein --> enzymes, pH, substrate & products: ileum
Endopeptidase/Exopeptidase/ Protease, pH 8.5, Proteins/ Polypeptides & Amino acids/Polypeptides
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Lipid --> enzymes, pH, substrate & products: duodenum
Bile salts/Lipase, pH 7, Lipids & Fatty acids/Glycerol
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Lipid --> enzymes, pH, substrate & products: ileum
Lipase, pH 8.5, Lipids & Fatty acids/Glycerol
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Small intestine adaptations
Very long (about 6 m in length). Lining is folded/on the surface of the folds are villi/epithelial cells have microvilli - all increase surface area. Absorption occurs by diffusion, facilitated diffusion & active transport. Active transport requires ATP s
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Small intestine - amino acid absorption & process
Amino acids are absorbed into epithelial cells by active transport. They move into the capillaries by facilitated diffusion.
The amino acids are water soluble so dissolve in the blood plasma
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Small intestine - glucose & process
Glucose passes into the epithelial cells with sodium by co-transport. Sodium moves to the capillaries by facilitated diffusion. Both diffusion and facilitated diffusion are slow so not all glucose can be absorbed by this method, some is absorbed by active
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Small intestine - fatty acid and glycerol absorption & process
Fatty acids and glycerol diffuse into the epithelial cells and then into lacteals.
Lacteals are part of the lymphatic system. The lymph system transports fat soluble molecules to the left subclavian vein near the heart
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What is the function of bile?
Emulsifies lipids, neutralises the stomach and maintains a pH. It also increases the surface area
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Why does each organ have a different pH in the digestive system?
Each enzyme has an optimum pH so each organ needs to have the correct pH for the enzyme
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In which part of the digestive system is digested food absorbed into the circulation?
ileum
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What are the 4 main functions of the gut?
ingestion, digestion, absorption, egestion
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What is the pH of the stomach?
pH 2
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What is contained with pancreatic fluid?
amylase, lipase, endopeptidase - trypsin
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Where is protein digested?
stomach, duodenum, ileum
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Where is starch digested?
mouth, duodenum, ileum
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How is the wall of the ileum adapted for aborption?
very long, large surface area, villi, the lining is folded, microvilli, mitochondria - ATP
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Small intestine - mineral and vitamin absorption
Minerals diffuse into the blood using diffusion, facilitated diffusion and active transport to dissolve into the plasma
Vitamins B and C are water soluble and are absorbed into the blood
Vitamins A, D and E are fat soluble and are absorbed into the lactea
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Secretion of inactive precursors
Pepsin and trypsin are secreted in their inactive forms to prevent them from digesting tissues of the body
E.g. pancreas and stomach
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Importance of emulsification of lipids
Increases surface area of lipids so increases rate at which they are digested by enzymes
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The large intestine: length
About 1.5 m long
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The large intestine: micro-organisms living in the colon - purpose
These bacteria are responsible for making vitamin K and folic acid
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The large intestine: food state & contents
By the time it reaches the rectum, the food is in a semi solid state (containing undigested cellulose, bacteria and sloughed off cells)
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Faecus (poo)
Semi solid material is expelled through the anus
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Other cards in this set

Card 2

Front

Digestion and absorption take place here in a long, hollow, muscular tube

Back

Processing food: The gut

Card 3

Front

Food is processed as it passes along the regions of the gut

Back

Preview of the back of card 3

Card 4

Front

Food is propelled along by peristalsis

Back

Preview of the back of card 4

Card 5

Front

Wave like contractions that happen in the oesophagus, stomach and intestines that act to propel food along

Back

Preview of the back of card 5
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