1. fermentation of organism in a bioreactor, extraction and chemical modification to increase pharmacological properties and antimicrobial efficacy.
2. Direct synthetic chemical manufacture
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When do we use oral antibiotics?
For community derived prescribed by the GP
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When do we use systemic route for antibiotics?
Patients with serious infections, who need hospitalisation; often unable to take the oral route
1. Growth begins
2. Antibiotic added at day 1
3. Antibiotic begins to kill cells
4. Two cells survive 3 days by stopping growth
5. One cell enlongates and divides
6. After 4 days one cell is adapted and grows
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What is bactericidal?
Kill bacteria
used when host defence mechanisms are impaired
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What is bacteriostatic?
Inhibit bacteria
Require host defence mechanisms to be intact to remove static pathogens
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Other cards in this set
Card 2
Front
How are antibiotics manufactured?
Back
1. fermentation of organism in a bioreactor, extraction and chemical modification to increase pharmacological properties and antimicrobial efficacy.
2. Direct synthetic chemical manufacture
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