controls the manufacture and distribution of all medicines for humans and animals
1 of 26
misuse of drugs act (1971, 2001, 2012)
regulates the drugs deemed to be dangerous or harmful
2 of 26
three classes of drugs
general sales list, pharmacy medicines and prescription only
3 of 26
the six rights
medication, route, patient, dose, documentation and time
4 of 26
patient group directives
not a prescription, written for groups of patients and can only be administered by the nurse who issued them
5 of 26
routes of administration
oral, intramuscular, subcutaneous, intravenous, transdermal, sublingual, rectal and vaginal
6 of 26
allergy
overreaction of the boys immune system
7 of 26
anaphylaxis
severe life threatening allergic reaction
8 of 26
pharmacokinetics
what the body does to the drug (absorption, distribution, metabolism and excretion)
9 of 26
pharmacodynamics
what the drug does to the body
10 of 26
absorption
how the drug enters the bloodstream. small intestines has a large surface area for absorption. IV drugs are delivered directly into circulation so no absorption is required
11 of 26
factors that affect absorption
drugs in liquid are absorbed faster. GI tract disorders can alter surface area. some drugs are absorbed better on an empty stomach
12 of 26
first pass effect
the metabolism of the drug during its first pass through the liver
13 of 26
bioavailability
the amount reaching circulation (the amount of the drug that will work)
14 of 26
distribution
how the drug is carried in the bloodstream to its target tissues
15 of 26
plasma protein carriers
many drugs temporarily bind to plasma protein carriers whilst in blood
16 of 26
bound drugs
have no pharmacological effect
17 of 26
unbound drugs
have pharmacological effect
18 of 26
metabolism
how the drug breaks down/is changed into a form that can be excreted. mainly occurs in the liver
19 of 26
two phases of metabolism
various chemical reactions that alter chemical properties of the drug and conjunction (turning the drug water soluble
20 of 26
factors that effect metabolism
age and liver disease affect liver enzyme levels. genetic differences in enzyme levels may exist. enzyme levels may be induced or inhibited
21 of 26
excretion/elimination
how the metabolised drug is removed from the body. mainly by urine
22 of 26
minor routes of elimination
skin, lungs and saliva
23 of 26
therapeutic range
may be narrow or wide (wider is safer) Aim to keep the drug levels in the therapeutic range
24 of 26
half life
indicates how often doses are needed. varies rapidly
25 of 26
crushing tablets
may disrupt the release properties of the drug with risks of toxicity
26 of 26
Other cards in this set
Card 2
Front
misuse of drugs act (1971, 2001, 2012)
Back
regulates the drugs deemed to be dangerous or harmful
Comments
No comments have yet been made