L4 - Roe - Calcium regulation 0.0 / 5 ? PharmacyCalcium regulationUniversityNone Created by: RscottqubCreated on: 01-04-19 21:35 calcium pools huge resevoir of Ca in the bones in the form of calcium phosphate 1 of 15 Total body calcium 1kg, 999g in bone , 1g in ECF 2 of 15 Free Ca in ECF comes from bone, diet(intestine), kidney reabsorption, from cells, bound calcium etc 3 of 15 Hormone systems in place to regulate Ca parathromone. Vit D, Calcintonin 4 of 15 Parathromone will increase Ca levels in ECF 5 of 15 Vit D will increase Ca levels in ECF 6 of 15 calcitonin will decrease Ca levels in ECF 7 of 15 Parathromone is stimulated by fall in ECF Ca level 8 of 15 Sources of Vit D (2) sunlight, diet 9 of 15 Active vit D Vit D needs to be hydroxylated twice to become active, once in liver , secondly in kidney 10 of 15 active vit D ... increases absorption of Ca from the gut 11 of 15 calcitonin reduces release of Ca from bone , preventing ECF levels rising 12 of 15 hypocalcaemia too little Ca in ECF , could be due to vit D def --> rickets 13 of 15 Hypercalcaemia too much Ca in ECF- due to Xs Ca in diet- or too much Vit D 14 of 15 ECF calcium is a membrane stabaliser- tends to block Na channels - reducing excitability 15 of 15
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