HD - Endocrine basics

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Describe paracrine type of action? With e.g.
Acts on neighbouring cells (histamine)
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Describe Autocrine type of action? With e.g.
Acts on itself (IL)
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Describe endocrine type of action? With e.g.
Release directly into blood stream to distant site (insulin)
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Describe neuroendocrine type of action. With e.g.
Release from a neurone directly into blood stream (DA inhibition of prolactin)
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What hormones are tyrosine derivatives?
Dopamine, adrenaline, thyroxine
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What is dopamine a precursor of?
Noradrenaline
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Examples of peptide hormones?
GnRH (10aa), GHRH (44aa), prolactin (198aa), insulin (51aa)
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Glycoprotein hormones are made up of what two chains?
Alpha and Beta
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Which chain, out of alpha and beta, is function specific and what is species?
Alpha - species, beta - function
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Examples of glycoprotein hormones?
LH, FSH, TSH, hCG
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Which type of release of GnRH leads to inhibition of FSH and LH release?
Sustained
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What are steroid hormones made from?
Cholesterol
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Which steroid hormones affect water and electrolyte balance?
Mineralcorticoid and aldosterone
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Which steroid hormones affect carb and protein metabolism?
Glucocorticoids and cortisol
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Do hormones act on inotropic receptors?
No
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What are five types of hormone release? With examples
Pulsatile (GnRH), circadian (24hr cycle, cortisol), diurnal (day, night cycle), Infradian (menstrual cycle), seasonal (prolactin)
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What types of hormones travel in free form?
Catecholamine and Peptide (therefore shorter half life) - largely hydrophilic. Steroid and thyroid hormones are lipothilic
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Where are steroid hormones stored?
They are not
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When are hormones biologically active?
When in free form
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Other cards in this set

Card 2

Front

Describe Autocrine type of action? With e.g.

Back

Acts on itself (IL)

Card 3

Front

Describe endocrine type of action? With e.g.

Back

Preview of the front of card 3

Card 4

Front

Describe neuroendocrine type of action. With e.g.

Back

Preview of the front of card 4

Card 5

Front

What hormones are tyrosine derivatives?

Back

Preview of the front of card 5
View more cards

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