Cancer

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  • Created by: Ellie2033
  • Created on: 09-05-24 14:12
P53 is what type of gene?
tumour suppressor
1 of 12
Mutations in RAS genes cause what?
rampant cell proliferation
2 of 12
A mutation that leads to the development of a hallmark of cancer is know of what?
driver mutation
3 of 12
Do passenger mutations have direct effect on the fitness of a tumour?
no
4 of 12
"Different cancers can be caused by mutations in different genes"
heterogenicity
5 of 12
tumour suppressor genes typically follow which inheritance pattern?
autosomal dominant
6 of 12
proto-oncogene genes typically follow which inheritance pattern?
autosomal recessive
7 of 12
successive acquisition of mutations which are then replicated and outcompete original genes
linear evolution
8 of 12
multiple genetically distinct clones emerge from a common ancestor
branched evolution
9 of 12
FAP is caused by mutations in which gene?
APC gene
10 of 12
Lynch syndrome (HNPCC) is caused by mutations in which gene?
mismatched repair genes
11 of 12
carcinomas are caused by mutations in which genes?
P53 genes
12 of 12

Other cards in this set

Card 2

Front

Mutations in RAS genes cause what?

Back

rampant cell proliferation

Card 3

Front

A mutation that leads to the development of a hallmark of cancer is know of what?

Back

Preview of the front of card 3

Card 4

Front

Do passenger mutations have direct effect on the fitness of a tumour?

Back

Preview of the front of card 4

Card 5

Front

"Different cancers can be caused by mutations in different genes"

Back

Preview of the front of card 5
View more cards

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