Block 7 Pharmacolog

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What is the effects of ethinylestradiol?
Suppresses FSH, causes maturation and release of egg
1 of 32
5a-Dihydrotestosterone has a higher addinity than testosterone. T or F?
True
2 of 32
Nandrolone is an anabolic steroid. What does it do?
Increase production of EPO
3 of 32
Alprostadil is a synthetic prostaglandin, What is its MOA?
Increases cAMP and PKA activation = relaxes penis arteries
4 of 32
Bicalutamide is an androgen antagonist. What does it treat?
Prostate cancer
5 of 32
Finasteride reduces Prostate size, whats its MOA?
Testosterone 5a-reductase inhibitor
6 of 32
Goserelin is a Leutenizing Hormone Releasing Hormone super agonist. This increases LH release - increasing androgen in men. Chronic administration = down regulation of LHRH and reduced androgen. What does it treat?
Prostate cancer
7 of 32
What are Medroxyprogesterone Acetate and Norethisterone?
Synthetic progesterones
8 of 32
Oestriol is a metabolite of oestradiol, produced in large amounts during when?
Pregnancy
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Name the NSAID whos reduced prostaglandin production = less pain
Methanamic acid
10 of 32
Tranexamic has what MOA?
Inhibits Activation of plasminogen to plasmin
11 of 32
What drug inhibits pancreatic lipase?
Olistat
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Bupropion has what MOA to act as a body weight control drug?
NA/D RI
13 of 32
Lorcaserin is a serotonin agonist that increases what production to increase saiety?
POMC
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Repaglinide promotes insulin release, whats its MOA?
SUR-1 agonist
15 of 32
Octreolide is a somatostatin agonist, what does it inhibit?
Glycogen phosyphorylase
16 of 32
What is a general mixture of pharmalogical pancreatic enzymes?
Pancreatin
17 of 32
Pioglitazone is an agonist at PPAR. What does it do?
Prevent glucose release and Reduces insulin resistance
18 of 32
Liraglutide promotes insulin release through being an agonist to which receptor?
GLP-1
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Ipragliflozin is a sodium glucose transport protein antagonist, what does SGLT2 do?
Reabsorbs glucose in the kidney
20 of 32
Bromocriptin/Cabergoline is an agonist for which NT?
Dopamine
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Metoclopramide is a dopamine agonist. Does it increase or decrease endocrine secretion?
Increase
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Carbimazole inhibits what enzyme, reducing iodination of T3/4
Thyroid peroxidase
23 of 32
Levothyroxine is a what agonist?
T4 thyroxine agonist
24 of 32
Protirelin is synphetic what?
TRH
25 of 32
Desmopressin is synthetic what?
ADH
26 of 32
Pegvisomant is a antagonist of what hormone, reducing cell growth?
Growth Hormone
27 of 32
Somatropin is a synthetic Human growth hormone. True or false?
True
28 of 32
Tetracosactide is an agonist for what?
ACTH
29 of 32
Clomiphene is a receptor agonist of what?
Oestrogen
30 of 32
What does oxytocin do?
Increase uterine contraction, maternal behaviours and sexual arousal
31 of 32
Atosiban inhibits uterine contraction via what MOA?
OXTR Antagonist
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Card 2

Front

5a-Dihydrotestosterone has a higher addinity than testosterone. T or F?

Back

True

Card 3

Front

Nandrolone is an anabolic steroid. What does it do?

Back

Preview of the front of card 3

Card 4

Front

Alprostadil is a synthetic prostaglandin, What is its MOA?

Back

Preview of the front of card 4

Card 5

Front

Bicalutamide is an androgen antagonist. What does it treat?

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Preview of the front of card 5
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