Bipolar

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What is the 1st line treatment for acute bipolar mania?
Haloperidol, olanzapine, quetipine or risperidone
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Which drug should not be given for mania?
Lamotrigine
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Which drug can be given as 1st prophylactic treatment long term for bipolar?
Lithium
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Which drug can be given as long term prophylactic treatment if unresponsive to lithium therapy?
Carbamazepine
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How long can it take for full prophylactic effect of Lithium?
6-12 months
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What treatment can be offered in severe mania which hasn't responded to other interventions?
ECT
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Antipsychotics can be used concomitantly with Lithium or Valproate in initial treatment of severe acute episodes of mania, true or false?
True
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After how long should patients medication be reviewed for their bipolar depression?
4 weeks after resolution of symptoms
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What is the MOA of typical antipsychotics that are high potency?
Inhibit D2 receptors in 4 pathways (mesolimbic, mesocortical, nigrostriatal and tuberoinfundibular)
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What is the MOA of atypical antipsychotics?
Block D2 receptors and serotonin receptor (5-HT2A) because serotonin can block dopamine release, therefore increasing dopamine levels
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Which atypical antipsychotic shouldn't be used in severe heart disease or neutropenia?
Clozapine
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Other cards in this set

Card 2

Front

Which drug should not be given for mania?

Back

Lamotrigine

Card 3

Front

Which drug can be given as 1st prophylactic treatment long term for bipolar?

Back

Preview of the front of card 3

Card 4

Front

Which drug can be given as long term prophylactic treatment if unresponsive to lithium therapy?

Back

Preview of the front of card 4

Card 5

Front

How long can it take for full prophylactic effect of Lithium?

Back

Preview of the front of card 5
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