HideShow resource information
  • Created by: Amh
  • Created on: 13-04-16 14:42
What defines a cat A agent can easily disseminate/be transmitted from person to person 2. high mortality 3. causes public panic 4. require special action for public health
1 of 59
What are some cat A diseases
Anthrax, smallpox, botulism, plague, tularaemia, ebola
2 of 59
What causes anthrax
bacillus anthracis
3 of 59
What causes small pox
variola virus
4 of 59
What causes botulism
clostridium botulinum
5 of 59
What causes the plague
Yersinia pestis
6 of 59
What causes tuleraemia
franciella tularensis
7 of 59
What are some cat B agents
Q fever, brucellosis, Ricin and toxins
8 of 59
what defines a cat B agent
1.. less easily disseminated, less morbidity and mortality, requires specific diagnostic care
9 of 59
What defines a cat c agent
emerging pathogens that could be enginered for mass dissemination, more easily availablem, can be modified for virulence
10 of 59
Give an example of a cat c path
yellow fever MDRTB hantavirus
11 of 59
Does bacilus anthracis sporulate?
12 of 59
Other characteristics of bacilus anthracis
gram positive rod, spores in soils, can lie dormant as a spore
13 of 59
Why is its ability to lie dormant as a spore important
Key to dissemination and therefore being a successful bioterrorist agent
14 of 59
Who is most likely to get anthrax
slaughterhouse workers - hoofed mammals are prone to bacilus anthracis
15 of 59
How is bacillus anthracis transmitted
1. Cutaneously via contact with spores. 2. via inhalation of spores , 3. via GI ingestion of spores
16 of 59
outline cutaneous anthrax
spore enters an abrasion, symptoms develop 1-7 days, then lesion goes through stages papule to ulcer to vesicle to black eschar
17 of 59
How quickly do symptoms develop in cutaneous anthrax
within 1-7 days no latency period
18 of 59
What are the stages of cutaneous anthrax
Papule ulcer vesicle to a black eschar
19 of 59
How does inhalational anthrax come about
inhalation of spores
20 of 59
What are the clinical stages of inhalational anthrax
1st stage is flu like symptoms. 2nd is breathing difficulty, shock, meningitis 50%
21 of 59
outline bacilus anthrax
larger spores lodge in throat and windpipe and others germinate between 1-60days, this produces toxins which cause tissue death and haemorrhage
22 of 59
what are the outcomes of anthrax
cutaneous 10% mortality - 1% mortality with treatment. Inhalational fatal
23 of 59
How do you diagnose Anthrax
Chest X Ray will show widened mediastinum, peripheral blood smear, blood cultures, and CSF cultures, ound cultures and post mortem
24 of 59
How do you treat anthrax
Ciprofloxacin (and other antibiotics from sensitivity tests) 60days treatment
25 of 59
Can we treat prophylacticly
yes with ciprofloxacin or doxycycline
26 of 59
what is small pox due to
variola virus
27 of 59
Is variola virus ds / ** RNA/DNA
ds DNA virus
28 of 59
When was small pox erradicated?
29 of 59
Where are the small pox stocks
30 of 59
How is small pox spread
person to person by slaiva
31 of 59
When are people most infectious
from the onset of rash through first 7-10 days
32 of 59
When does the risk of transmission end
when the scabs fall off
33 of 59
What are the clinical features of small pox
signs and symptoms typically develop within 7-17 days , acute onset of high fever fatigue head and backaches, 22 days later rash appears
34 of 59
what is the fatality percent
35 of 59
what does the rash look like
flat red lesions macules papules progress to pus-y one's called vesicles, lesion begins to crust in the secund week
36 of 59
how do you diagnose small pox
lymphocytosis, thrombocytopenia,,whole blood 4 pcr, antigen detection, vesicle fluid for EM or PCR,
37 of 59
how do you manage smallpox
infectious disease team, immune staff, strict protective clothing, no specific treatment, vaccine contact
38 of 59
What is the death due to
toxaemia and immune complexes from viral antigens
39 of 59
What is botulism due to
a neurotoxin produced by clostridium botulinum
40 of 59
what are the 3 forms of naturally
foodbourne, wound and infant
41 of 59
how quickly do signs and symptoms develop
24-72 hours
42 of 59
What are the symptoms of botulism
bulbar muscle paralysis, (double vision blurred speech drooping eyelids difficulty swallowing) progression to paralysis, respiratory failure death
43 of 59
What does botulism depend on
rate and amount of toxin absorbed ``
44 of 59
how do you diagnose botulism
classical triad; symmetrical descending flaccid paralysis with bulbar palsy, afebrile patient, clear sensorium. Toxin assay; blood, stool, gastric aspirate
45 of 59
what is the treatment for botulism
botulinum antitoxin
46 of 59
What are the chaacteristics of Yersinia pestis
gram negative rod
47 of 59
What are the forms of Yersinia pestis
Bubonic, primary septicaemic, secondary pneumonic
48 of 59
where does the plague occur
south west usa
49 of 59
how is plaguetransmitted
person to person by respiratory droplets
50 of 59
What are the clinical features of pneumonic plague
incubation 2-4 days, fever cough difficulty breathing and haemoptysis, GI symptoms, pneumonia
51 of 59
How do you diagnose oneumonic plaque
chest x ray, gram stain, culture of sputum, blood, lymph nodes
52 of 59
What is tularaemia caused by
Francisella tularensis
53 of 59
what are the characteristics of Francisella tularensis
gram negative, coccobacilus
54 of 59
What are the 5 forms of the isease
ulceroglandular, glandular, pleuopulmonary, typhoidal, oropharyngeal
55 of 59
How can transmission occur naturally
tick bites, exposure to infected animals, ingestion of contaminated food or water, inhalation of infetious aerosols
56 of 59
when was tularaemia used as a weapon
by soviet union in 1970s
57 of 59
what are the clinical features off tularemia
acute onset of febrile illness, but respiratory symptoms do not usually predominate
58 of 59
How do you diagnose tularemia
chest x ray, culture sputum blood pleural fluid, serology
59 of 59

Other cards in this set

Card 2


What are some cat A diseases


Anthrax, smallpox, botulism, plague, tularaemia, ebola

Card 3


What causes anthrax


Preview of the front of card 3

Card 4


What causes small pox


Preview of the front of card 4

Card 5


What causes botulism


Preview of the front of card 5
View more cards


No comments have yet been made

Similar Biology resources:

See all Biology resources »See all micro resources »