basic pharmacokenetics

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  • Created by: anna888
  • Created on: 20-02-23 16:01
iv cmax vs oral, why?
iv straight into blood-immediate and higher cmax. oral goes through 1st pass metabolism- bits of drug are lost and takes time
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what is F of iv
100%
2 of 7
what is exponential function for plasma conc vs time graph
Ct= C0 x e^-kt
3 of 7
what is reverse of e
the natural log ln
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what does the auc represent, 2 ways to calcuate
total drug conc in plasma over whole time. use trapezoids or total of f
5 of 7
what is bioavailability equation
f= (auc oral/auc iv) x (dose iv/dose oral)
6 of 7
what f is good?
over 85%
7 of 7

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Card 2

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what is F of iv

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100%

Card 3

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what is exponential function for plasma conc vs time graph

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Card 4

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what is reverse of e

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Card 5

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what does the auc represent, 2 ways to calcuate

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