B3

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  • Created by: ireynolds
  • Created on: 02-05-17 16:15
Whats a nucleus? (animal cell)
It contains DNA in the form of chromosomes.
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What is a cytoplasm?
Gel-like substance where most of the cell's chemical reactions happen.
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What is a cell membrane?
It holds the cell together and controls what goes in an out.
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What is a ribosome?
It's where proteins are synthesised.
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What are mitochondria?
Where most of the reactions involved in respiration take place. As respiration provides energy for cell processes, cells that need lots of energy contain many mitochondria.
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Why do liver cells contain many mitochondria?
As they carry out many demanding metabolic reactions.
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Why do muscle cells contain many mitochondria?
As they need energy to contract and cause movement.
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What features do plant cells have?
Nucleus, cytoplasm, chloroplasts, cell wall, vacuole and cell membrane.
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What are chloroplasts? (pc)
Where photosynthesis happens.
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What is the cell wall? (pc)
Made of cellulose and supports the cell.
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What is a vacuole? (pc)
A relatively large structure that contains cell sap, a weak solution of sugar and salts.
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What features do bacterial cells have?
Cytoplasm, cell membrane, cell wall. They have a single circular strand of DNA that floats on the cytoplasm, instead of a nucleus.
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What are chromosomes?
Long molecules of coiled up DNA.
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What shape is DNA?
A double helix.
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What are each of the 2 strands of DNA made up of?
Small groups called nucleotides.
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What does each nucleotide contain?
A small molecule called a base.
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What are the 4 bases in DNA?
A, C, G & T
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How are the DNA strands kept wound tightly together?
As each base forms cross links to a base on the other strand.
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What bases pair with each other?
A & T C & G =called complementary base-printing.
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What did Crick and Watson do in 1953?
First scientists to build a model of DNA.
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What data from other scientists did they use to help them understand the molecule of DNA?
X-ray data showing it's a double helix formed from 2 chains. Other data showing the bases occurred in pairs.
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How does DNA replicate itself?
DNA copies itself every time it divides. 1) It unzips to form 2 single strands. 2) New nucleotides join on using comlementary base-pairing. 3) Result= two double-stranded molecules of DNA that are identical to the original.
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What controls the production of proteins?
DNA
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What's a section of DNA that codes for a particular protein called?
Gene.
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What are proteins made up of?
Chains of molecules called amino acids, each different protein has its own particular number and order of amino acids.
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What does the shape of a protein give it?
A function.
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What decides the order of amino acids in a protein?
The order of bases in a gene.
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What is each amino acid coded for by?
By a sequence of three bases in the gene.
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How are amino acids joined together to make proteins?
By following the order of bases in the gene. 1) there's a sequence of bases. 2) the cell reads the genetic code. 3) it puts the amino acids together.
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Where are proteins made in the cell?
In the cell cytoplasm by tiny structures called ribosomes.
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How does the cell get the code from the DNA to the ribosomes?
By using the molecule mRNA which is made by coping the code from DNA, the mRNA acts as a messenger between the DNA and ribosome, carrying the code between to two.
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Why can't DNA move out of the cell nucleus?
Because it's too big.
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Why do different types of cell have different functions?
Because they make different proteins.
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Why do cells only make certain proteins?
Because only some of the full set of genes is used in any one cell. Some genes are 'switched off' which means the proteins they code for aren't produced.
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What do genes that are 'switched on' do?
Determine the function of the cell. E.G; in a muscle cell, only the genes that code for muscle cell proteins are switched on.
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What are the four main types of proteins?
Enzymes, carrier molecules, hormones, structural proteins.
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What do carrier molecules do?
Used to transport smaller molecules E.G; haemoglobin binds to oxygen molecules and transports them round the body.
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What do hormones do?
Used to carry messages around the body E.G; insulin released to regulate blood sugar levels.
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What do structural proteins do?
They are physically strong. E.G; collagen strengthens connective tissues.
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What are enzymes?
Biological catalysts that speed up chemical reactions in the body.
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Advantages of enzymes?
Reduce the need for high temperatures (which can damage cells) and we only have them to speed up the useful chemical reactions in the body.
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Does every different biological reaction have its own enzyme designed for it?
Yes.
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Why are enzymes different?
Each enzyme is coded for by a different gene and has a unique shape which it needs to do its job.
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What's the substrate?
The molecule changed in a biological reaction.
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What's an enzymes active site?
The part where it joins on to its substrate to catalyse the reaction.
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What does an enzyme having a high specificity for their substance mean?
That they're really picky and only work with one substrate.
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Why do enzymes have a high specificity for their substrate?
Because, for the enzyme to work, the substrate has to fit the active site, if the substrate doesn't match the active sites shape, then the reaction won't be catalysed. Called the 'lock and key' mechanism, as they fit perfectly.
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What does changing the temperature do to an enzyme-catalysed reaction?
Changes the rate of the reaction.
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What does a higher temperature do to the rate of an enzyme-catalysed reaction?
A higher temp increases the rate at first, as more heat means the enzymes and the substrate particles have more energy, making the enzymes and the substrate particles move about more and have a higher collision rate.
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What effect does a lower temp have on it?
Lower collision rate and so a slower reaction.
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What happens if the temperature gets too hot?
Some of the bonds holding the enzyme together will break. The enzyme will become denatured.
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What is a denatured enzyme?
Where it loses it's shape and it's active site doesn't fit the shape of the substrate anymore. Therefore it can't catalyse the reaction and stops; the enzyme can't function. The change in shape is irreversible.
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What is an enzymes optimum temperature?
When the reaction goes fastest, just before it gets too hot and starts the denature.
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What's human enzyme optimum temperature?
About 37degrees which is body temperature.
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What effect does ph have on enzymes?
If the ph is to high or low, it interferes with the bonds holding the enzyme together, changing the shape of the active site and denaturing it.
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What's an optimum ph for enzymes?
Theph that they work best at. Usually ph7; neutral.
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What's pepsin?
An enzyme used to break down proteins in the stomach,working best at ph2 so it's suited for the acidic conditions.
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What does a Q10 value for a reaction show?
How much the rate changes when the temp is raised by 10degrees.
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Equation for the Q10 value?
Q10 = rate at higher temperature/rate at lower temp.
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What would a Q10 value of 2 mean?
That the rate doubles when the temp is raised by 10degrees. And 3 means trebles ect...
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What are gene mutations?
A change in the DNA base sequence.
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What could happen if a mutation occurs within a gene?
Could stop the production of the protein the gene normally codes for, or mean a different protein is produced instead.
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Bad effect of a mutation occuring in a reproductive cell?
The offspring might develop abnormally or die at an early stage of development.
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Bad effect of a mutation occuring in a body cell?
The mutant cells can start to multiply in an uncontrolled way and invade other parts of the body; cancer.
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Possible benefits of a mutation?
A protein is produced that's an improvement of what it was supposed to be, giving the organism a survival advantage over the rest of the population, and can pass it on to it's offspring.
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Why are some mutations neither harmful nor helpful?
As the don't change the protein being coded for, so have no effect on the organism.
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How do mutations occur spontaneously?
When a chromosome doesn't copy itself properly.
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What increases the chance of mutation if you're exposed to it?
1) Ionising radiation(x-rays, uv, radioactive substances) the greater the dose, the higher the chance. 2) Certain chemicals called mutagens, if they cause cancer they're called carcinogens.
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What's an example of a carcinogen?
Cigarette smoke .
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Advantages of being a multicellular organism?
Be bigger, cell differentiation, more complex.
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Advantages of being able to be bigger?
Can travel further, get nutrients in variety of different ways, fewer things can eat or squash you.
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Advantages of cell differentiation?
Can have different cells for different jobs, and cells can be specially adapted to do the jobs E.G; carrying oxygen in blood.
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Advantages of being complex?
Have specialised organs, different shapes,behaviour and can be adapted specifically to their particular environment.
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What does a multicellular organism have to have?
Specialised organ systems.
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What types of specialised organ systems do they have to have?
A system to communicate between cells(nervous system), system to supply cells with nutrients they need(circulatory system), a system that controls exchange of substances with environment(respiratory system).
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What is mitosis?
When a cell reproduces itself by splitting to form two identical offspring.
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When does mitosis happen?
When you want identical cells(When you want to grow,m or to replace worn-out cells to repair tissues).
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What happens to the DNA in mitosis?
1) Before mitosis starts the DNA in the cell is replicated. 2) The the beginning, the DNAcoils into double armed chromosomes which are exact copies of each other. 3) The chromosomes line up at the centre of the cell and divide as fibres pull them ...
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continued....
...divide as cell fibres pull them appart. 4) the2 arms of each chromosomes go to opposite poles of the cell. 5) Membrames form around each of the sets of chromosomes.
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6) The cytoplasm divides leaving 2 genetically identical cells. 7) process repeats to divide again.
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What's meiosis?
Cell division in which gametes are formed.
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What are gametes?
Sex cells, eggs and sperm.
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What are the body cells of mammals?
Diploid.
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What does diploid mean?
That each of the organisms body cells has two copies of each chromosome in it's nucleus. One from the father and one from the mother.
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What kind of cells are haploid in mammals?
Gametes.
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What does a cell being haploid mean?
That they only have one copy of each chromosome.
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Why are gametes haploid?
So when the egg and sperm combine, they'll form a cell with the diploid number of chromosomes.
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Explain the process of meiosis?
1)DNA replicates and curls to form double-armed chromosomes. 2)The chromosomes arrange themselves into pairs. 3)In the first division the pairs split up and the chromosomes in each pair move to opposite cell poles...
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4)In the two knew cells there's no pairs and it's a mixture of the mammals mum and dads genes totally 23 chromosomes instead of 46. 5)In the second division each chromosome splits apart, and one arm end ends up in a different cell= 4 new cells.
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5) Each of the 4 cells in genetically different as the chromosomes get shuffled up, leaving each gamete with a random selection of half the chromosomes.
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What's a zygote?
A diploid cell formed in fertilisation when male and female gametes combine.
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What are the characteristics of the zygote controlled by?
The combination of genes on its chromosomes. As it's inherited features from two parents it will show features of both, but not exactly like either of them.
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What is a sperm cells function?
To transport the male's DNA to the female's egg.
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How are sperm cells adapted for their function?
Are small with long tails to assist the swim to the egg, lot's of mitochondria to provide energy for the swim. Have an acrosome at the head which can release the enxymes needed to digest their way though the egg cells membrane.
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How do animals grow?
Grow until reach a finite size. Growth happens by cell division.
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How do plants grow?
Grow continuously. They grow in height by cell enlargement (elongation). Growth by cell division happens in areas of the plant called meristems(tips of roots and shoots).
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What's cell differentiation?
Process by which a cell changes to become specialised for a job.
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Does differentiation occur in animal cells?
Yes but lost at an early stage.
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Does differentiation occur in plant cells?
Yes and the ability is never lost.
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What are undifferentiated cells?
Ones that can develpoe into other types of cells, tissues and organs depending on instruction, they're named stem cells.
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Where are stem cells found?
In early human embryos, or in adult human bone marrow , but they aren't as vertisile and can only turn into a few types of cells.
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How are stem cells already used in medicine?
Bone marrow transplants to cure blood disorders,
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What are possible uses for human stem cells in medicine?
EXtracting stem cells from embryos and growing them, to eventually grow tissues to treat medical conditions. E.G; nerve cells for brain damage and spinal injuries, skin cells for skin grafts, known as stem cell therapy.
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Why are people against stem cell research?
As they feel human embryos shouldn't be used in experiments as they're potential human lives.
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Why are people for stem cell research?
Curing existing patients who are already suffering is more important than the embryos. The embryos used in research are unwanted ones and would otherwise be destroyed.
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Explain the method of measuring growth by length?
Just measuring length or height of an organism.
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Advantages of this method?
Easy and no skilled workers or specialist equipment needed.
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Disadvantages of this method?
Only tells you about one change, missing out changes in width, diameter, number of branches ect...
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Explain the method of measuring growth by wet mass?
Weigh the plant or animal as it comes.
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Advantages of this method?
Easy to measure.
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Disadvantages of this method?
Wet mass is very changeable. E.G; plant will be heavier if it's recently rained as absorbed lots of water, and heavier if eaten or drank.
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Other cards in this set

Card 2

Front

What is a cytoplasm?

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Gel-like substance where most of the cell's chemical reactions happen.

Card 3

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What is a cell membrane?

Back

Preview of the front of card 3

Card 4

Front

What is a ribosome?

Back

Preview of the front of card 4

Card 5

Front

What are mitochondria?

Back

Preview of the front of card 5
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