Addison's disease 0.0 / 5 ? MedicineEndocrine disordersEndocrinologyUniversityOther Created by: FarhanaAhmedCreated on: 07-01-17 21:30 What is the an alternative name for Addison's disease? Hypoadrenalism 1 of 17 What is Addison's disease? Impairment of adrenal cortex due to loss of adrenal hormones 2 of 17 What are the 3 adrenal hormones? Glucocorticoids, mineralocorticoids, androgens 3 of 17 How many people are affected by Addison's disease in the UK? 1 in 15,000 people. 4 of 17 Which patient is most at risk of Addison's disease? Females between ages 30-50 years. 5 of 17 At what stage does onset of disease occur? After 90% of the adrenal cortex in destroyed 6 of 17 Which 2 hormones are responsible for most of the symptoms of the disease? Cortisol and aldosterone 7 of 17 What may be the common cause in MEDCs? Auto-immune disease of renal cells 8 of 17 What may be the likely cause in LEDCs? Infection of adrenal glands due to poor sanitation 9 of 17 What are some alternative reasons for Addison's disease? Malignant tumour in adrenal glands, combination of infections, trauma, medication, vascular disturbances or metabolic effects 10 of 17 Name some common symptoms of Addison's disease Skin pigmentation, weight loss, fatigue, hypotension, loss of axillary hair, confusion, muscle weakness, cardiac atrophy, tachycardia 11 of 17 What is the reason for increased skin pigmentation during Addison's disease? Because MSH is a cleaved product of the polypeptide POMC when ACTH is cleaved 12 of 17 What is the treatment? Cortisone, DHEA and fludrocortisone hormone therapy + increase sodium ion intake during dehydration 13 of 17 What is prednisone? Prodrug of cortisol to replace cortisol 14 of 17 What does Ovomax do? Replace levels of DHEA androgens. 15 of 17 Describe Addison's crisis When a patient abruptly withdraws from hormone replacement therapy leading to hypoglycaemia, hyperkalaemia and hypotension 16 of 17 What is the treatment for Addison's crisis? Intravenous saline solution, dextrose (sugar), fludrocortisone and hydrocortisone 17 of 17
Comments
No comments have yet been made