20.3- Regulation of transcription and translation

?
  • Created by: Megan2413
  • Created on: 27-03-18 12:17
What will stop as a result of transcription being stopped?
Gene expression of the gene being transcribed
1 of 16
What controls translation?
siRNA
2 of 16
What controls transcription?
Transcriptional factors
3 of 16
What are transcriptionl factors?
A molecule which 'switches on' (expresses) a gene and binds to the promotor region on the base sequence on the DNA
4 of 16
Which enzyme is stimulated for transcription as a transcriptional factor has bound to a promotor region?
RNA Polymerase
5 of 16
When the gene isn't expressed, what isn't activated and what is then prevented?
The promotor region on the DNA sequence hence no transcription occurs
6 of 16
What is an example of a hormone which can affect the activity of a transcriptional factor?
Oestrogen
7 of 16
Why can oestrogen diffuse through the phospholipid bilayer of the plasma membrane?
It is a small, lipid soluble molecule
8 of 16
Once in the cytoplasm, where does the oestrogen molecule bind and why?
To the receptor site on the transcriptional factor because their shapes are complimentary to one another
9 of 16
Upon binding of oestrogen, what changes in the transcriptional factor?
The shape of the DNA binding site of the transcriptional factor hence it is activated
10 of 16
Where does the transcriptional factor now diffue?
Into the nucleus via a nuclear pore
11 of 16
What happens with the transcriptional factor in the nucleus?
The DNA binding site binds to a specific base sequence on the DNA- transcription is now stimulated
12 of 16
Which molecule can inhibit the translation of an mRNA molecule?
siRNA
13 of 16
What does siRNA stand for?
Small interferring RNA
14 of 16
Describe the steps by which siRNA inhibits translation
1. An enzyme cuts large double-stranded RNA into smaller section called siRNA 2. One of the two siRNA strands combine with an enzyme 3. The siRNA molecule guides the enzyme to an mRNA molecule by pairing up its bases with the complimentary ones -->
15 of 16
on a section of mRNA 4. Once in position, the enzyme cuts the mRNA into smaller sections 5. The mRNA is no longer capable of being traanslated into a polypeptide hence the gene hasn't been expressed
-->
16 of 16

Other cards in this set

Card 2

Front

What controls translation?

Back

siRNA

Card 3

Front

What controls transcription?

Back

Preview of the front of card 3

Card 4

Front

What are transcriptionl factors?

Back

Preview of the front of card 4

Card 5

Front

Which enzyme is stimulated for transcription as a transcriptional factor has bound to a promotor region?

Back

Preview of the front of card 5
View more cards

Comments

No comments have yet been made

Similar Biology resources:

See all Biology resources »See all Gene expression resources »